"Alphalyse developed and qualified an LC-MS method for monitoring host cell proteins in our MVA-BN® platform vaccine candidate" Iben Schildt Sørensen, Director QC-K Bavarian Nordic, Denmark "Alphalyse's HC
MiRs are secreted in blood plasma and thus may report on systemic aberrations at an early stage via liquid biopsy analysis. We present a method for multiplexed single-molecule detection and quantification of a selected panel of miRs. The proposed assay does not depend on sequencing, requires less...
in June 2022, scientists at the Indian Institute of Science, Bangalore, developed a unique class of synthetic peptides or miniproteins, and the researchers claim that it had the potential to neutralize viruses like SARS-CoV-2.
(Thomas and Butler, 1977). All of the core histones are small basic proteins (~100-150 aa) with relatively large amounts (>20%) of lysine and arginine residues, stabilizing the chromatin structure by interacting with the phosphate backbone of DNA. The amino acid sequence and length of the...
(1) Evaluation of the Immunoprotective Capacity of Five Vaccine Candidate Proteins against Avian Necrotic Enteritis and Impact on the Caecal Microbiota of Vaccinated BirdsAnimals (Basel)October 26, 2023Sara Heidarpanah, Alexandre Thibodeau, Valeria R. Parreira, Sylvain Quessy, Mariela Segura, Marcelo ...
“Development of measures for quantification of µs-PEF effects on microtubules”), with the results presented in Fig.4e. As shown in the graph, the value of the MT displacement index speed was proportional to the applied pulse voltage. This finding is understandable, because the electric ...
excitation with light at a specific wavelength and quantification of the emission light at higher one at about the same time. The wavelength selection is accomplished via filters or monochromators. The signal intensity is linear to the concentration of a fluorophore and is accordingly used to quanti...
The use of a microfluidic “lab-on-a-chip” technique for the separation and quantification of milk proteins is described and compared with traditional sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). The microfluidic chip technique could separate all major milk proteins when stand...
Quantification studies on N2fixation by legumes in the tropics andsubtropicshave revealed a large range in estimates of the % Ndfa, e.g, 0–95% for soybean, 8–89% for cowpea, 22–92% for groundnut, and 10–88% for pigeonpea [19]. The amounts of N fixed by these legumes ranged fr...
Examples of such potential future applications of MS protein assays in clinical labs include screening and diagnosis of hemoglobin variants by MS analysis of intact proteins, measurement of protein modifications as markers of metabolic disorders or xenobiotics exposure, and quantification of proteins in ...