网络L-氨基己二酸半醛脱氢酶 网络释义 1. L-氨基己二酸半醛脱氢酶 主题词注释库... ... L-Amino Acid Oxidase L-氨基酸氧化酶L-Aminoadipate-Semialdehyde DehydrogenaseL-氨基己二酸半醛脱… kns.chkd.cnki.net|基于 1 个网页
A soluble enzyme that catalyzes the oxidation of l-α-aminoadipate δ-emialdehyde to l-α-aminoadipic acid in the presence of NAD + has been isolated and characterized from human liver. This enzyme l-α-aminoadipic δ-semialdehyde oxidoreductase has been found to be localized in the cytosol usi...
Kinetic studies were carried out for histidine-tagged saccharopine reductase from Saccharomyces cerevisiae at pH 7.0, suggesting a sequential mechanism with ordered addition of reduced nicotinamide adenine dinucleotide phosphate (NADPH) to the free enzyme followed by l-α-aminoadipate-δ-semialdehyde (l-...
分子式C6H9NO2 分子量127.14100 精确质量127.06300 PSA49.66000 LogP0.12990 l-aasa英文别名 L-aminoadipate semialdehyde 暂无推荐供应商。我要出现这里 相关化合物:更多... L-Asparagine Monohydrate (15N2) 287484-32-6 L-Uridine 26287-69-4 L-Proline, 1-cyano-, methyl ester (9CI) ...
L-pipecolic acid metabolism in human liver: L-alpha-aminoadipate delta-semialdehyde oxidoreductase.| Chang, YF., et al. 1990. Biochim Biophys Acta. 1038: 300-5. PMID: 2160277 Inhibitors of the NMDA-Nitric Oxide Signaling Pathway Protect Against Neuronal Atrophy and Synapse Loss Provoked by l-al...
This enzyme oxidizes l-pipecolic acid with concomitant production of H 2O 2 in the peroxisome of the normal human liver. The immediate product of l-pipecolic acid oxidation has been identified as l-α-aminoadipate δ-semialdehyde. This reaction product was directly, and also after conversion to...
Saccharopine accumulation leads to mitochondrial damage and functional loss which is induced by saccharopine dehydrogenase (SDH) mutations of α-aminoadipate semialdehyde synthase (AASS)-1 inC. elegans. 体内研究 Saccharopine accumulation induces mitochondrial damage and progressive postnatal growth retardation ...
Substrate specificity of CsiD was then examined with 5-aminovalerate, 2-aminoadipate, 2-ketoadipate, glutarate, succinate, adipate, glutaryl-CoA, and l-lysine as the test substrates and 2-KG as the co-substrate. CsiD seems to have a narrow substrate specificity, only glutarate being rapidly ...
our data, as lysine levels decreased in both PAECs and PASMCs. Interestingly, the lysine degradation pathway was identified in our (network-based) analyses, and lysine metabolism is a source of NADH production through the functions of sacchariopinedehydrogenaseand α-aminoadipate semialdehyde ...
the aldehyde product is instable (Tufvesson et al., 2011): Lysε:αKG transamination forms α-aminoadipate-δ-semialdehyde and Glu, while α-aminoadipate-δ-semialdehyde undergoes spontaneous intramolecular imine formation to form 1-piperideine-6-carboxylic acid (Soda et al., 1968) (see Table 3...