Cite this entry (2004). Kv-channels. In: Encyclopedic Reference of Molecular Pharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29832-0_908 Download citation .RIS .ENW .BIB DOIhttps://doi.org/10.1007/3-540-29832-0_908 Publisher NameSpringer, Berlin, Heidelberg Print ...
A family of potassium channels (Kv) are expressed in neurons when they are damaged. Blockers of these channels protect neurons from several different types of insults, whether due to disease or trauma. Furthermore, blockers of these channels promote neurite outgrowth in neural progenitor cells. ...
Wang MC, Liu ZH, Liang SP (2013a) Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels. Biochemistry 52:7439–7448 ...
Kv channels contribute to NO- and ANP-induced relaxation of a rat conduit artery Y Tanaka,G Tang,K Takizawa,... 被引量: 7发表: 2006年 Kv7 Channels in Cyclic-Nucleotide Dependent Relaxation of Rat Intra-Pulmonary Artery action of nitric oxide, but its contribution when dilation is evoked by...
KV7.2/7.3 activator; displays anticonvulsant properties 4519ML 213 KV7.2 and KV7.4 channel opener 4777ML 277 Selective KV7.1 (KCNQ1) potassium channel activator; augments IKscurrent 3062NS 1643 KV11.1 (hERG) channel activator; antiarrhythmic
Kv7.2/7.3 channels Axonal Kv7.2/7.3 channelsAxonal Kv7.2/7.3 channelsKCNQ2KCNQ3action potentialM-currentaxon initial segmentnode of Ranvierepileptic encephalopathyRapid energy-efficient signaling along vertebrate axons is achieved through intricate subcellular arrangements of voltage-gated ion channels and ...
Deglycosylation of Shaker KV channels affects voltage sensing and the open–closed transition 喜欢 0 阅读量: 14 作者:LR Angelica,H Miguel 摘要: 150 mM NaCl, 1 mM PMSF, 0.5 mM MgCl2, 0.5 mg/ml lysozyme, and 25 μg/ml deoxyribonuclease I). Cells were lysed by using Emul- siFlex-C5 (...
说明: Blocker of KV1.5 channel and IKur current 别名: Diphenyl phosphine oxide-1 化学名: [1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphine oxide 纯度:≥99% (HPLC) 说明书 引用文献 (5) 评论(1) 生物活性 技术数据 溶解性 计算器 说明书 参考文献 ...
Studies the inhibitory effects of endothelin 1 on voltage-gated potassium (Kv) channels in hypoxic hypertensive rat pulmonary artery myocytes. Cell isolation and myosin staining; Effect of chronic hypoxia on voltage-gated postassium current; Role of ET-1-mediated pulmonary artery vasoconstriction in ...
Voltage-gated K+ channels (Kv) represent the largest family of genes in the K+ channel family. The Kv1 subfamily plays an essential role in the initiation and shaping of action potentials, influencing action potential firing patterns and controlling neuronal excitability. Overlapping patterns with dif...