Kv-channelsdoi:10.1007/3-540-29832-0_908Kv-channels is an abbreviation of voltage-gated potassium channels. K stands for potassium and v for voltage.Springer Berlin Heidelberg
Targeting KV channels rescues retinal ganglion cells in vivo directly and by reducing inflammation. Channels. 2010;4(5):337–46.Koeberle PD, Schlichter LC: Targeting KV channels rescues retinal ganglion cells in vivo directly and by reducing inflammation. Channels (Austin) 2010, 4:337-346....
Similarly, inhibition of K V channels in vitro (4-aminopyridine, 1mM) or in silico increased λ by 41% and 21%, respectively. Immunofluorescence microscopy demonstrated expression of BK Ca , Kv1.5, Kv2.1, but not Kv1.2, in VSMCs of rat mesenteric terminal arterioles. Our results demonstrate...
Although Kv1.1 channels, which finely tune neuronal excitability, may have a role in seizures initiation, the relations between the loss of Kv1.1 and the emergence of TDS remain unclear. Indeed, previous studies using chronic − up to two weeks − infusion of anti-LGI1 antibodies in the...
Activation of voltage-dependent K+ (Kv) channels modulates cellular excitability in several physiological systems including neuronal and cardiac cells. Given recent progress in structure determination and in computation technology, molecular dynamics (MD) simulation analyses have become a valuable tool in ...
Voltage-gated K+ channels (Kv) represent the largest family of genes in the K+ channel family. The Kv1 subfamily plays an essential role in the initiation and shaping of action potentials, influencing action potential firing patterns and controlling neuronal excitability. Overlapping patterns with dif...
Kv7/KCNQ/M-channels in rat glutamatergic hippocampal axons and their role in regulation of excitability and transmitter release. J Physiol 2006; 576 (Pt 1): 235–56Vervaeke K, Gu N, Agdestein C, Hu H, Storm JF (2006) Kv7/KCNQ/M channels in glutamatergic hippocampal axons and their role...
The effects of Kv3.3 on the actin cytoskeleton are mediated by the binding of the cytoplasmic C terminus of Kv3.3 to Hax-1, an anti-apoptotic protein that regulates actin nucleation through Arp2/3. A human Kv3.3 mutation within a conserved proline-rich domain produces channels that bind Hax...
Down-regulation of delayed rectifier K+ channels in the hippocampus of seizure sensitive gerbils. In order to confirm the species-specific distribution of voltage-gated K (Kv) channels and the definitive relationship between their immunoreactivities and... SM Lee,JE Kim,JH Sohn,... - 《Brain ...
Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells. Am J Physiol Cell Physiol 286, C611... T Speake,JD Kibble,PD Brown - 《Am J Physiol Cell Physiol》 被引量: 69发表: 2004年 Kvl.l and Kvl.3 channels contribute to the ...