Furthermore, KLRG1− CD127+ cells isolated within a week after infection exhibit a gene expression profile that is related to that of memory cells isolated after clearance of the infection (Best et al., 2013). Expression of CD127 is vital for MPCs, as this is the receptor for IL-7, ...
than KLRG1−CD127+CD8+T-cells. Therefore, the modulation of CD8+T-cell differentiation in FL by PI3K inhibitors may promote a more effective antitumor immune response and thus improve the clinical prognosis of lymphoma patients [121]. KLRG1 may also be a marker for monitoring antitumor response...
than KLRG1−CD127+CD8+T-cells. Therefore, the modulation of CD8+T-cell differentiation in FL by PI3K inhibitors may promote a more effective antitumor immune response and thus improve the clinical prognosis of lymphoma patients [121]. KLRG1 may also be a marker for monitoring antitumor response...
the ratios of CD4+T cells, CD4+CD127+T cells, CD8+T cells, CD8+CD127+T cells, and CD8+KLRG1+T cells did not change significantly in post-NAC versus pre-NAC, reflecting the limited immune activation
NAC resulted in an increase only of CD20(+) B cells, whereas NAPC increased the infiltration of CD20(+) B cells, CD4(+) T cells, CD4(+)CD127(+) T cells, CD8(+) T cells, CD8(+)CD127(+) and CD8(+)KLRG1(+) T cells. Synergistic increase in B and T cells promotes favorable ...
Expression of KLRG1 and CD127 defines distinct CD8 + subsets that differentially impact patient outcome in follicular lymphoma Background CD8 T-lymphocyte subsets defined by killer lectin-like receptor G1 (KLRG1) and CD127 expression have been reported to have an important role in... H Wu,X Ta...
Combination treatment augmented the number of activated CD86(+) DCs in the draining lymph nodes and increased the percentage of KLRG1(+) CD127(-)CD8(+... E Schaedler,C Remy-Ziller,J Hortelano,... - 《Vaccine》 被引量: 6发表: 2017年 PTSD is associated with an increase in aged T cell...
在急性感染期间,抗原特异性CD8 T细胞扩增并分化表达为KLRG1highCD127low的CD8记忆前体效应细胞(MPEC)以及表达为KLRG1lowCD127high的短寿效应细胞(SLEC)。7CD127是白细胞介素7的受体,可通过增加抗凋亡因子表达来决定细胞的寿命;因此,MPEC的CD127表达水平高于SLEC。8相应图例显示了使用针对KLRG1和CD127的荧光偶联抗体在...
However, the dramatic reduction in KLRG1hi cells caused by loss of Id2 remained in the absence of Bim, such that Id2/Bim double-deficient cells form an exclusively KLRG1lo CD127hi memory precursor population. Thus we describe a role for Id2 in both the survival and differentiation of ...
Increased Expression of TIGIT/CD57 in Peripheral Blood/Bone Marrow NK Cells in Patients with Chronic Myeloid Leukemia. The expression of CD57 correlates with replicative senescence and maturity for human NK cells; therefore, the increase in TIGIT on PB NK cells together ... D Yao,L Xu,L Liu...