(no. 321428), Sigrid Juselius Foundation, Finnish Foundation for Cardiovascular Research, Centre of Excellence of Cardiovascular and Metabolic Diseases and the Academy of Finland (to M.L.). Work in the laboratory of J.A.E. is funded by the CNIC and a grant by Ministerio de Ciencia, ...
Two new LiquiChip bead-based xMAP assay kits, from Qiagen NV, facilitate research in drug discovery, cell signaling, oncogenesis, apoptosis, and immune disorders. Optimized immobilized substrates enable detection of a wide range of Tyrrosine and Serine/Threonine kinase activities without the need for...
Mosley for laboratory and animal management; C. Richter and N. Teja for antibody production; and the National Clinical Trial & Research Center at National Taiwan University Hospital, and the Bioinformatics and Biostatistics Core, Research Center for Medical Excellence at National Taiwan University, ...
Enzyme Research Tools Sino Biological offers a variety of research tools (e.g.recombinant proteins,antibodies,ELISA kits,cDNA clones) to study proteases, kinases, and other enzymes. Our protease-related products are available to study cysteine proteases, aspartic proteases, metalloproteases, and serine...
Although the expression amounts had been reduced when compared with LNP-modRNA delivery into the liver, our data show the ability of LNPs to functionally deliver modRNA therapeutics to the damaged myocardium, which keeps great promise for modRNA-based cardiac therapies.In this research, we investigat...
Tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-10, IL-1β enzyme-linked immunosorbent assay (ELISA) kits, recombinant human IL-10 and monoclonal anti-IL-10, anti-IL-1 and anti-IL-18 neutralizing antibodies (Abs) were purchased from R&D Systems (McKinley Place, MN, USA). ...
Ovarian cancer (OC) ascites consist in a proinflammatory tumor environment that is characterized by the presence of various cytokines, chemokines and growth factors. The presence of these inflammatory-related factors in ascites is associated with a more
W. Surrogate-light-chain silencing is not critical for the limitation of pre-B cell expansion but is for the termination of constitutive signaling. Immunity 27, 468–480 (2007). Article CAS PubMed Google Scholar Nakayama, J. et al. BLNK suppresses pre-B-cell leukemogenesis through inhibition...
In recent years, interest has focused on the role of protein phosphorylation in the control of the cell cycle; a number of cellular proto-oncogenes encode members of the serine/threonine kinase family and it has become increasingly clear that certain serine/threonine kinases function as key compon...
These procedures may be conducted using a variety of commercially available kits, such as those provided by Pharmacia & Upjohn (Kalamazoo, Mich.), Promega (Madison, Wis.), and U.S. Biochemical Corp. (Cleveland, Ohio). Suitable reporter molecules or labels which may be used for ease of ...