本次泰它西普亮相于 2024 ERA 国际会议的 4 项小样本量临床试验初步证实,泰它西普可降低 IgA 肾病患者的蛋白尿,同时维持肾功能的稳定,且在安全性方面表现良好,这些研究结果表明泰它西普在 IgA 肾病领域中具有潜在的治疗价值,但未来仍需更大规模的前瞻性研究来进一步探索这些发现。目前,泰它西普正在进行的用于 IgA...
◎不同基线 eGFR 不会对达格列净治疗的主要结局产生影响。 ◎SGLT2i 治疗 CKD,初始 eGFR 一过性下降(< 30%)不增加不良反应的发生。 总体而言,在临床应用 SGLT2i 时,面对 IgA 肾病患者、不同基线 eGFR 的患者,以及应用初期 eGFR 一过性下降的情况,医生们均可以一定程度上打消相关顾虑。SGLT2i 在 CKD 治疗...
““I have IgA Nephropathy. Can I get off dialysis by Toxin-Removing Treatment?” Recently a kidney failure patient consulted our online doctor for such a question. If you have been fed up with the current treatment, you can try Toxin-Removing Treatment, which can help you a lot in improv...
The kidneys are bean-shaped organs (about 11 cm x 7 cm x 3 cm) that are located against the back muscles in the upper abdominal area. They sit opposite each other on both the left and right sides of the body; the right kidney, however, sits a little lower than the left to accommod...
[13]Complement in IgA Nephropathy and Lupus Nephritis: Role in Pathogenesis and Implications for Treatment [14]Antigens Underlying Glomerular Diseases: Diagnostic, Pathogenic, and Clinical Implications 更多肾病临床知识哪里看? 快...
IgA Nephropathy and Creatinine Stable at 3.5 to 3.7: Should I Worry Can I Normalize Creatinine 2.1 with IgA Nephropathy What Is the Radical Treatment for FSGS Nephrotic Syndrome and Hypertension: Causes and Treatment Will My Kidneys Fail Within One or Two Years With IgA Nephropathy ...
Background: IgA nephropathy (IgAN) is a common primary glomerulonephritis leading to end-stage renal disease. Living donor kidney transplantation (LDKT) is considered a favorable treatment option, but IgAN recurrence rates and the impact on outcome is unclear. In the present study, we ...
IgA nephropathy The most common form of glomerulonephritis worldwide. It is characterized by the deposition of IgA-containing immune complexes in the mesangial compartment of glomeruli, which leads to mesangial cell-proliferative lesions, haematuria and proteinuria. Pauci-immune focal necrotizing glomerulonep...
Multiple ligand-receptor connections were also detected in glomerular cells of IgA nephropathy (IgAN) mice. Glomerular endothelial cells occupied the dominant position by activating and recruiting leukocytes at the initial phase of IgAN.135Among primary glomerular cell types, mesangial cell-expressed Slit3...
For treatment of kidney patients, hiPSC-derived renal-like cells could be implanted (top, right) into the kidneys. Either renal-like progenitor cells, as generated by various protocols (Fig. 3, top), or more mature renal-like cell types could be used. Also structurally intact or dissociated...