kidney failurerenal replacement therapy (RRTRRT modalityhematologic malignancylight chain deposition disease (LCDDTransplant centers have historically considered a history of multiple myeloma (MM) a contraindication to kidney transplantation (KT) due to high recurrence rates and poor allograft survival. ...
Kidneys play an important role, as they filter out waste from your blood. When acute kidney failure happens, higher levels of waste can build up and chemicals in your blood can be unbalanced. This type of kidney failure happens quickly, but it can be reversed with treatment. If you have s...
Many different symptoms can occur during kidney failure. Usually someone with kidney failure will have a few symptoms of the disease, though sometimes none are present. Possible symptoms include: a reduced amount of urine swelling of your legs, ankles, and feet from retention of fluids caused by...
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post-...
Multiple myeloma (MM), a plasma cell cancer, is associated with many health challenges, including damage to the kidney by tubulointerstitial fibrosis. We develop a mathematical model which captures the qualitative behavior of the cell and protein populat
Chronic kidney disease (CKD)—or chronic renal failure (CRF), as it was historically termed—is a term that encompasses all degrees of decreased renal function, from damaged–at risk through mild, moderate, and severe chronic kidney failure. CKD is a wor
Certain cancers (incidental carcinoma,lymphoma,multiple myeloma, renal cell carcinoma, Wilms tumor) HIVinfection Vesicoureteral reflux (This is a urinary tract problem.) Past kidney transplant (graft failure) Rheumatoid arthritis Chronic kidney failure is associated with complications that can be debilitati...
Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post-renal causes of kidney failure include bladder obstruction, prostate problems, tumors,...
Among the renal complications, the most frequent nephrological consultation is done for progressive renal failure in patients with multiple myeloma. Twenty-five or thirty years ago, tumor lysis syndrome and acute uric acid nephropathy were common. Since the advent and use of allopurinol, acute urate...
(They weigh at least 15% less than they should.) That can lead to a lack of water, electrolytes, and salt in the body, which can cause chronic kidney disease and, eventually, kidney failure. This is especially true for people who binge-eat and purge (vomit or use laxatives) to get ...