chronic kidney failuregraft survivalkidney transplantationmortalitymultiple myelomarecurrenceBONE-MARROW-TRANSPLANTATIONRENAL-TRANSPLANTATIONLIGHT-CHAINCELL TRANSPLANTATIONIntroduction: Data on kidney transplantation (KTx) outcomes of patients with multiple myeloma (MM) are very limited. Methods: We investigated the ...
This can be caused by an infection, autoimmune disease (such as lupus, vasculitis, and scleroderma), multiple myeloma, chemotherapy drugs, antibiotics, or other toxins Acute Kidney Failure Risk Factors Most of the time, kidney failure happens along with another medical condition or event. If you...
Abbreviations: CI, confidential interval; KFRT, kidney failure with replacement therapy; MM, multiple myeloma. a Fine and Gray model 1 is adjusted for age and sex. b Fine and Gray model 2 is adjusted for age, sex, smoking, alcohol consumption, regular exercise, and low income. c Fine and...
Chronic kidney disease (CKD)—or chronic renal failure (CRF), as it was historically termed—is a term that encompasses all degrees of decreased renal function, from damaged–at risk through mild, moderate, and severe chronic kidney failure. CKD is a wor
Multiple myeloma (MM), a plasma cell cancer, is associated with many health challenges, including damage to the kidney by tubulointerstitial fibrosis. We develop a mathematical model which captures the qualitative behavior of the cell and protein populat
(They weigh at least 15% less than they should.) That can lead to a lack of water, electrolytes, and salt in the body, which can cause chronic kidney disease and, eventually, kidney failure. This is especially true for people who binge-eat and purge (vomit or use laxatives) to get ...
Failure, Loss, End-Stage Renal Disease (RIFLE) [21] and Acute Kidney Injury Network (AKIN) [22] have been proposed and validated. Recently, severity of AKI staged by RIFLE criteria (OR = 2.04 Failure stages versus Risk and Injury stageP= 0.06) has been reported as associated with marginal...
Johnson WJ, Kyle RA, Pineda AA, O'Brien PC, Holley KE: Treatment of renal failure associated with multiple myeloma. Plasmapheresis, hemodialysis, and chemotherapy. Arch Intern Med 150:863–869, 1990 | Article | PubMed | ChemPort | Wahlin A, Lofvenberg E, Holm J: Improved survival in mul...
We retrospectively analyzed the natural history of 78 patients with MM and AKI between July 1995 and December 2010. RIFLE criteria solely on the basis of the serum creatinine standard were applied to stage the severity of AKI as Risk, Injury, or Failure. Among the patients at stage Risk, ...
Cast nephropathy is a form of progressive renal failure that occurs in the setting of multiple myeloma. Although it was well known that immunoglobulin light chains participate integrally in the process,26–30 dissecting the pathogenesis of this complex problem proved difficult. More recently, evidence...