Ki-67 Score Is Not Predictive of Overall Survival, Disease-Free Survival or Metastasis in Estrogen Receptor Positive, Her2 Negative, Lymph Node Negative Breast Cancers 来自 国家科技图书文献中心 喜欢 0 阅读量: 16 作者:M Hiskey,P Mendoza,C Neely,C Sonmez,C Zhang,Y Liu,MT Siddiqui,C Cohen,X...
The range of Ki 67 score was 0 to 90%. Mean value of Ki 67 was 31.86% and median was 30%. A statistically significant correlation was observed between size (P=0.037), grade (P < 0.0001) and Nottingham Prognostic Index (P < 0.0001) with Ki 67 scores.No statistically significant ...
Ki-67 was scored as the percentage of positive tumor cell nuclei by counting a range of 400–500 cells (depending on the cellularity of the specimen), including also hot spot areas. The optimal cut-off value for Ki67 was defined by statistical analysis; however we also applied the 20 and...
To evaluate the prognostic significance and clinicopathologic correlation of proliferative activity in patients with hepatocellular carcinoma, Ki-67 antigen expression was examined using immunohistochemical staining with monoclonal antibody MIB1. Seventy-two patients (65 men, 7 women; age range 24-77 years...
This cohort study of patients with breast cancer investigates whether Ki-67 expression correlates with the 21-gene recurrence score (RS) and whether high
Nevertheless, high KI-67 was found to be associated with immediate pathological complete response in the neoadjuvant setting, with an LOE of II-B. The REMARK score improved over time (with a range of 6–13/20 vs. 10–18/20, before and after 2005, respectively). KI-67 could be ...
Mean Ki-67 index was 41.8% (SD 15. 7%, range 8.2-84.2%). Differentiated had a higher Ki-67 index than undifferentiated , although other clinicopathological variables, including lymph node metastasis and depth of invasion showed no correlation with Ki-67 index. In the undifferentiated , Ki-67...
The Ki-67 LI was averaged at three representative areas on the invasive side of the tumor and presented as a percentage score (range 0–100%) of positive tumor cells. This was used to divide the patients into two groups (those with > 20% positive tumor cells and those with less)....
The median Ki-67 score was 40%, with an interquartile range of 24–52%. Mann–Whitney U-test for non-parametric data and Spearman rank correlation for continuous and ordinal variables. Kaplan–Meier curves were con- structed to estimate cancer-specific survival according to Ki-67 score and ...
The carcinomas showed a wide range of Ki-67 labelling, reflecting a variation in proliferative activity. The tumour labelling index ranged from 1 to 80 per cent positivity: there was also heterogeneity of labelling within many of the tumours. There was no correlation between Ki-67 derived ...