Three pathologists with breast expertise each performed a blinded review with 3 different manual scoring methods [estimated (EST), unweighted (UNW), and weighted (WT) (WT recommended by the International Ki-67 in Breast Cancer Working Group)]. Quantitative image analysis (QIA) using the HALO ...
[9] Nakajima N, Oguchi M, Kumai Y, et al. Clinical outcomes and prognostic factors in patients with stage II-III breast cancer treated with neoadjuvant chemotherapy followed by surgery and postmastectomy radiation therapy in the mod- ern treatment era[J]. Adv Radiat Oncol, 2018, 3(3): 271...
Breast, Cancer, Ki67, Manual, Automated, AssessmentBackgroundBreast cancer is by far the most frequent cancer among women. The proliferative index, Ki-67, is more and more taken into consideration for treatment decisions. However, the reliability of the established Ki-67 scoring is limited. ...
The proliferation marker Ki-67 is one of the most controversially discussed parameters for treatment decisions in breast cancer patients. The purpose of th
Objectives: Ki-67 has been proposed to be used as a surrogate marker to differentiate luminal breast carcinomas (BCs). The purpose of this study was to determine the utility of and best approaches for using tissue microarrays (TMAs) and Ki-67 staining to distinguish luminal subtypes in large...
虽然目前仍无法确定原发病灶与脑转移病灶Ki-67指数的变化是否与患者的生存期有关,但这为今后的研究提供了方向。 参考文献 Chen JX; Zhou JM; Zhang HQ, et al. Conversion of ER, PR, HER2 and Ki-67 and Prognosis in breast cancer metastases to the brain. 10.21203/rs.3.rs-1692389/v1....
Ki -67 was 50.91%,wihich showed to be correlated to the size,histologic grade and metastasis of lymphnode in breast cancer.Conclusion Ki- 67 protein expression is closely related to pathologic characterstics in breast cancer,It can be used as an index for maligent degree in breast can- ...
Introduction Ki-67 expression is a biomarker for proliferation. Its prognostic value is recognized in breast cancer (BC) patients with negative axillary nodes, but is less clear in BC patients with positive axillary lymph nodes. Metho
Inwald EC, Klinkhammer-Schalke M, Hofstädter F, et al. Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry. Breast Cancer Res Treat. 2013;139(2):539-552. doi:10.1007/s10549-013-2560-8 PubMed...
Ki-67 expression in operable breast cancer: a comparative study of immunostaining and a real-time RT-PCR assay. Cyclin E expression in operable breast cancer quantified using real - time RT - PCR: a comparative study with immunostaining[ J]. Jpn J Clin Oncol,... P Potemski,E Puciennik,...