In 1975, the main active ingredient of khat, cathinone, was identified, and found to be structurally related to and with effects similar to amphetamines and other psychostimulants. Animal studies on the neurobiology of khat are sparse and sporadic, being a neglected area of research in the ...
‘Legal highs’ – an emerging epidemic of novel psychoactive substances” by Zawilska. This chapter will focus on the use of khat and its effects on brain function and health. How khat use remained for so long low on the global drug of abuse radar, the isolation, and structural ...
This review will cover the, phytochemistry, pharmacokinetics of the active ingredients-cathinone, cathine, norephedrine, neurochemistry, effects on cognitive and executive functions as well as its ability to produce dependency in the user. Whether it is an innocuous cultural practice or a ...
Metabolic Brain DiseaseAlbert W. Nyongesa , Jemimah A. Oduma , Motohiro Nakajima , Hesbon O. Odongo , Pius A. Adoyo , Mustafa al’Absi . (2014) Dose-response inhibitory effects of purified cathinone from khat (Catha edulis) on cortisol and prolactin release in vervet monkeys (Chlorocebus ...
The leaves of plant khat (Catha edulis) are widely consumed by people of East African countries, Yemen and many other parts of the world for their pleasurable and stimulating effects, because of its reported toxicity of unknown etiology. The objectives of this study was to evaluate the effect ...
Leach KR, Rogers N: Mapping the effects of khat (catha edulis) and tobacco on the human brain: a biological illustration supporting the common pattern of dual substance use among khat chewers. Oral presentation. Germany: First European Khat Research Program Conference, Goethe Universitat, Frankfurt...
Acute effects of a khat extract on the rat electroencephalogram. J Ethnopharmacol. Jul-Aug 1988;23(2-3):291-298.Saleh, M., H. Mekkawy & F. el-Komy (1988): Acute effects of a khat extract on the rat electroencephalogram. J. of Ethnopharmacology (Jul.-Aug.) 23/2-3: 291-298....
The effects of this treatment on selected organs, including the brain, hippocampus, heart, and ovaries, were assessed using various measurements and analyses. RESULTS (IF A CASE STUDY ENTER NA). Results: Results: The antioxidant evaluation showed a significant increase in MDA levels in the khat ...
Results: The effects of khat and CoQ10 on the weights of brain, liver, kidney and spleen was determined. Administration of khat decreased the levels of RBCs and its subtypes (MCV, MCH, RDW-SD and RDW-CV), a clear indicator of khat-induced normochromic microcytic anemia. White blood ...
Objective This study sought to determine whether chronic exposure to khat (Catha Edulis, Forsk) increases the vulnerability to the toxic effects of manganese (Mn2+), when co-exposed.Methods Three (3)-week-old forty (40) Swiss albino mice were randomly divided into four groups (n = 10). ...