Herein with Streptomyces roseosporus as a model, we showed that crotonylation is widespread on key enzymes for various metabolic pathways, and sufficient crotonylation in primary metabolism and timely elimination in secondary metabolism are required for proper Streptomyces metabolism. Particularly, the ...
[Part 1: Biological Sciences] || Inactivation of Key Metabolic Enzymes by Mixed-Function Oxidation Reactions: Possible Implication in Protein Turnover and ... E. R. Stadtman, "Oxidation of proteins by mixed-function oxidation systems: implication in protein turnover, ageing and neutrophil function...
Metabolic remodeling is now widely regarded as a hallmark of cancer, but it is not clear whether individual metabolic strategies are frequently exploited by many tumours. Here we compare messenger RNA profiles of 1,454 metabolic enzymes across 1,981 tumours spanning 19 cancer types to identify enzy...
Additional metabolic alterations identified are depicted by orange arrows. (B) Model depicting the role of PDH and ETFDH in metabolic phenotypes associated with IR. 3.7. Biological validation of in silico results in cultured mouse myocytes To determine if alterations in flux through the enzymes ...
enzymes with statistically significant coordinated changes in the abundance of surrounding metabolites were identified. Given the high inter-connectivity of metabolic networks, key enzymes are not necessarily topological neighbors of identified metabolites, as assumed in that work. Instead, enzymes at ...
Attention was paid to some brush border bound enzymes found in the digestive tract; then, some of the main enzymes known to control the nutritional metabolism in animal tissues were investigated to define the metabolic pattern of the species and the relative importance of key tissues with respect...
Those with the greatest representation by unique sequences were for ''metabolic pathways'' (5,406 counts, 28.09%). Our transcriptome revealed 156 Unigenes that encode key enzymes in the flavonoid biosynthesis pathway including CHS, CHI, F3H, FLS, DFR, etc. MISA software identified 2,762 ...
Based on the observation that mammary gland is secretory in nature, with properties similar to those of mucosal surfaces42, a view that has also been supported by the murine case43, we assumed that some of the enzymes involved in mucin biosynthesis would also be active in the production of ...
In this study, using the15N labeling method, it was found that nano-selenium could promote plant nitrogen metabolism and photosynthesis by increasing the light energy capture capacity and the activities of key enzymes of the nitrogen metabolism process, leading to an increase in alfalfa nitrogen ...
Abstract The vast and versatile pharmacological effects of medicinal plants are basically dependent on their phytochemical constituents. Generally, the phytochemical constituents of plants fall into two categories based on their role in basic metabolic processes, namely primary and secondary metabolites. Prima...