Cancer stem cells (CSCs), the subpopulation of cancer cells, have the capability of proliferation, self-renewal, and differentiation. The presence of CSCs is a key factor leading to tumor progression and metastasis. Extracellular vesicles (EVs) are nano-sized particles released by different kinds o...
1). These contents of exosomes can be used as prognostic markers and/or graded basis for cancer progression. It also regulates tumor growth, metastasis, angiogenesis, and mediates drug resistance in tumor cells.16 Some research process of exosomal components like proteins and noncoding RNAs will ...
New Analysis Identifies Key Markers in Pancreatic Cancer Progressiondoi:10.1097/01.COT.0001083644.59333.d1Mark L. FuerstWolters Kluwer Health, Inc.Oncology Times
To understand how different types of EVs affect cancer development, accurate nomenclature is essential. The International Society for Extracellular Vesicles (ISEV) proposed the Minimal Information for Studies of Extracellular Vesicles (“MISEV”) guidelines in 2014, which were updated four years later [...
expression of functional molecules such as IFN-γ, scarce proliferation, and also arrested cell cycle, due to an increase of the related proteins, P16 and P21. During the remodeling of the immune system with age, changes in immune cell markers are mainly characterized by the loss of CD27 an...
including the ability to self-renew and differentiation that give rise to heterogeneous, differentiated cancer cells making up the bulk of the tumour. Due to this similarity, CSCs are commonly characterised by the expression of surface markers associated with stem cells, such as CD133, CD44, CD90...
The impact of efferocytosis-related genes (ERGs) on the diagnosis of colorectal cancer (CRC) remains unclear. In this study, efferocytosis-associated biomarkers for the diagnosis of CRC were identified by integrating data from transcriptome sequencing an
we all know that the best option for any patient, for any stage of pancreatic cancer, is still a clinical trial. Not only should we encourage enrollment, but we need to make it very easy to access clinical trials. I do not want a patient to be put on hold on the telephone for hours...
23,24,25 Besides being nutrients essential for cell growth, in the context of cancer, metabolites represent sensitive markers of major alterations in cancer cell metabolism and contribute to oncogenic signaling. Lipid metabolism alteration is considered as another hallmark of cancer cells since lipid ...
of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Several studies have investigated the role of midkine as a cancer biomarker for the detection, prognosis, and management of cancer, as well as for monitoring the response to cancer treatment. ...