i.e. dispose of cellular waste, and generate new energy by reusing their own components. Disruption of the autophagy mechanism is thought to contribute to the development of several diseases. Therefore, this knowledge can play an important role in our understanding of the onset and treatment...
Cell-mediated immunity (CMI) is concerned with the elimination of cells that are modified by, for instance, infection with viruses 1. The specific operators of CMI are the thymus-derived lymphocytes (T cells), which recognize viral (or other non-self) components presented in the context of se...
Increased sexual activity reduces male immune function in Drosophila melanogaster This "cost" hypothesis predicts a tradeoff between immune defense and other components of fitness. In particular, a tradeoff between immunity and sexually ... KA Mckean,L Nunney - 《Proc Natl Acad Sci U S A》 被引...
The inflammasome: a danger sensing complex triggering innate immunity. The NOD-like receptors (NLR) are a family of intracellular sensors of microbial motifs and 'danger signals' that have emerged as being crucial components o... V Pétrilli,C Dostert,DA Muruve,... - 《Current Opinion in Im...
MICE GIVEN A HUMAN IMMUNE SYSTEM IMPLANT CALLED KEY TO PROMISING RESEARCHRichard A. Knox, Globe Staff
The mammalian immune system implements a remarkably effective set of mechanisms for fighting pathogens1. Its main components are haematopoietic immune cells, including myeloid cells that control innate immunity, and lymphoid cells that constitute adaptiv
As the intricacies of transcription and translation have been increasingly defined, anticancer therapeutic efforts have been initiated that are directed at correcting or inhibiting core components of the spliceosome in the cancer cell. The future holds great promise that research into the dysregulation of...
The process by which the membrane and protein components of synaptic vesicles are recovered from the plasma membrane after neurotransmitter release (via endocytosis) and used to regenerate new synaptic vesicles. Trans-Golgi network A membrane compartment downstream of the endoplasmic reticulum in the secr...
The purpose of the digestive system is to break down food into components the body can use, like glucose for energy, protein for building and repairing cells, and extracting vitamins, minerals and amino acids for cell function. The digestive system begins with the mouth, where teeth mash food...
The results of the GO analysis showed that the biological process changes of DEGs were significantly enriched in keratinization, epidermal development, and epidermal cell differentiation, and that the changes in the cell components were mainly in the keratinized envelope, spindle, and mesosome, whereas...