In the early 20th century, it was discovered that a diet primarily composed of fats could replicate the effects of starvation. These favorable outcomes of the ketogenic diet (KD) have been attributed to its influence on the production of ketones, including β-hydroxybutyrate, acetoacetate, and ...
The ketogenic diet (KD) switches cell energy metabolism from carbohydrates to fatty acid and amino acid oxidation1, from which ketone bodies, such as β-hydroxybutyrate (BHB), acetone, and acetoacetate (AcAc), are generated2. A consensus is yet to be reached regarding whether physiologic effects...
β-hydroxybutyrate reduces reinstatement of cocaine conditioned place preference through hippocampal CaMKII-α β-hydroxybutyrylation. Cell Rep. 41, 111724 (2022). Article CAS PubMed Google Scholar Nasser, S. et al. Ketogenic diet administration to mice after a high-fat-diet regimen promotes weight...
β-hydroxybutyrate reduces reinstatement of cocaine conditioned place preference through hippocampal CaMKII-α β-hydroxybutyrylation. Cell Rep. 41, 111724 (2022). Article CAS PubMed Google Scholar Nasser, S. et al. Ketogenic diet administration to mice after a high-fat-diet regimen promotes weight...
The ketogenic diet (keto diet) is a diet high in fat and low in carbs. Read on to learn about ketosis, and learn about the safety, health benefits, and risks of the ketogenic diet.
Thurston JH, Hauhart RE, Schiro JA. Beta-hydroxybutyrate reverses insulin-induced hypoglycemic coma in suckling-weanling mice despite low blood and brain glucose levels. Metab Brain Dis 1986;1:63–82. DeDeyn PP, Marescau B, MacDonald RL. Epilepsy and the GABA-hypothesis: a brief review and...
BHB (Beta-Hydroxybutyrate):A chemical made in the body that helps you feel energized when the body isn’t getting enough carbohydrates or sugars. B-Complex Vitamins:A group of nutrients that help to maintain a well-rounded diet. Electrolytes:Essential minerals—like calcium, sodium, and potassium...
3What is ketogenic diet? Ketogenic dietor keto diet is a low-carbohydrate high-fat diet that generatesketone bodiesor lipid-derived molecules produced through theketogenesisprocess, includingacetoacetate, beta-hydroxybutyrate and acetone (Egan and D'Agostino, 2016;Romano et al., 2017;Mullins et al....
diet, the FO-KD was most effective at reducing lung nodules. Correlating with this, mice on the FO-KD had low blood glucose and the highest β-hydroxybutyrate level, lowest liver fatty acid synthase/carnitine palmitoyl-1a ratio and a dramatic increase in fecal Akkermansia. We found no liver ...
ketogenic diet in the treatment of Alzheimer’s disease. The results showed that patients achieved sustained physiological ketosis (12-week mean beta-hydroxybutyrate level: 0.95 ± 0.34 mmol/L). Compared with the usual diet, patients on the ketogenic diet increased their mean within-...