The high-fat, low-carbohydrate ketogenic diet (KD) is an effective clinical treatment for epilepsy in juveniles, especially for drug-resistant seizures. The KD results in elevated production of ketone bodies (KB's), such as beta-hydroxybutyrate (β-HB), which are thought to have anticonvulsant...
Beta-hydroxybutyrate (BHB) is a ketone body and has recently been reported to exert anti-inflammatory effects via inhibition of NLRP3 inflammasome. Here, we investigated the potential antidepressant and anti-inflammatory effects of BHB on rats exposed to acute and chronic stress. We examined the ...
About β-Hydroxybutyrate β-Hydroxybutyrate (BHB, 3-hydroxybutyrate) is an endogenous ketone body that accumulates during periods of fasting, calorie restriction and prolonged exercise. It is created via a multi-step process involving the break-down of fatty acids into acetyl-CoA, conversion to ...
BCP can achieve these benefits without fasting, although results appear to be enhanced with a low carbohydrate or ketogenic diet. Furthermore, BCP protects against muscle loss by increasing glucose absorption through GLUT4 receptors and stimulating mitochondria glycolysis in muscle tissue. In muscle cell...
It is the exogenous ketogenic salt which shortly called BHB Salt Ca and engages with ketogenic diet. People also use number 3 to replace beta, so it got another name as 3-Hydroxybutyrate Prevents bone degradation by stopping the production of osteoclasts (cells that break down bone) in subjects...
The ketone body component includes beta-hydroxybutyrate, acetoacetate, or both. The beta-hydroxybutyrate is R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, or both. When the ketone body component is S-beta-hydroxybutyrate, the 1,3-butanediol is R-1,3-butanediol, S-1,3-butanediol, or both. ...
The ketogenic diet (KD) has been successfully used as a treatment for IS. This study was designed to test whether beta-hydroxybutyrate (BHB), a major metabolite of the KD, is effective in an animal model of IS.Yum, Mi-SunLee, MinyoungWoo, Dong-CheolKim, Dong WookKo, Tae-SungVelisek...
The ketogenic diet (KD) is increasingly popular amongst sub-fertile women trying to conceive, and results in elevated maternal ketone levels, including beta-hydroxybutyrate (bOHB). The impact of high bOHB levels on embryonic development, physiology, and developmental programming remains unknown. Aim: ...
Here, we investigated the effect of the ketogenic diet mimetic beta-hydroxybutyrate (BHB) on the expression of genes regulating mitochondrial biogenesis ( Ppargc1a , Nrf1 , Tfam) , quality control ( Sqstm1 ), functioning of the antioxidant system ( Nfe2l2 , Gpx1 , Gpx3 , Srxn1 , Txnrd...
Beta-hydroxybutyrate (BHB)SchizophreniaMK-801Sensorimotor gatingSociabilityImpaired cerebral glucose metabolism is a core pathological feature of schizophrenia. We recently demonstrated that a ketogenic diet, causing a shift from glycolysis to ketosis, normalized schizophrenia-like behaviours in an acute N-...