beta-Ketoacyl-acyl carrier protein (ACP) synthase III (the fabH gene product) condenses acetyl-CoA with malonyl-ACP to initiate fatty acid biosynthesis in the dissociated, type II fatty acid synthase systems typified by Escherichia coli. The accumulation of malonyl-acyl carrier protein (ACP) fol...
Branched-chain DSF-family signalsPathogenesisThe 3-ketoacyl-ACP synthase III (FabH), a key enzyme for bacteria growth, catalyses the last step of the initiation of bacterial fatty acid synthesis. Rice bacterial blight is caused by the pathogenXanthomonas oryzaepv.oryzae(Xoo), which is widely ...
The 3-ketoacyl-ACP synthase (KAS) III proteins are one of the most abundant enzymes in nature, as they are involved in the biosynthesis of fatty acids and natural products. KAS III enzymes catalyse a carbon–carbon bond formation reaction that involves the α-carbon of a thioester and the ...
英文名β-ketoacyl-[acyl-carrier-protein] synthase III 英文别名更多 生物活性 描述参与植物和细菌中游离(或II型)脂肪酸生物合成系统。与EC 2.3.1.41(β-酮酰基ACP合酶Ⅰ)和ec2.3.1.179(β-酮酰基ACP合酶Ⅱ)相比,该酶特别使用CoA硫酯而不是酰基ACP作为引物。除上述反应外,该酶还可以催化EC 2.3.1.38,[酰基...
Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis. Beta-ketoacyl-acyl carrier protein synthase III (FabH), the most divergent member of the family of condensing enzymes, is a key catalyst in bacterial fatty... X ...
CAS号[1048648-42-5]化源网提供[β-ketoacyl-[acyl-carrier-protein] synthase II]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。
The abbreviations used are: STPK, Ser/Thr protein kinase; ACP, acyl carrier protein; FAS-I, eukaryotic type I fatty acid synthase; FAS-II, prokaryotic type II fatty acid synthase; PDIM, phthiocerol dimycocerosate; GST, glutathione S-transferase; KAS, β-ketoacyl-ACP synthase; MS, mass ...
ACP1 is a small, acidic protein that functions as the central acyl group carrier in type II fatty-acid synthase systems. The ACPs are rod-shaped proteins with a preponderance of acidic residues organized into four α-helices (3, 4, 5, 6, 7). The acyl intermediates are attached to the ...
ACP synthase (condensing enzyme-like) calledbioZclustered with the biotin ring-forming genes16(Fig.2a). BioZ proteins have ~35% sequence identity with theE. coliandStreptomyces coelicolorFabH 3-ketoacyl-ACP (acyl carrier protein) synthase III (KAS III) proteins, which catalyze the initial ...
Carbon-carbon bond forming reactions are essential transformations in natural product biosynthesis. During de novo fatty acid and polyketide biosynthesis, β-ketoacyl-acyl carrier protein (ACP) synthases (KS), catalyze this process via a decarboxylative