15-keto-PGE2inflammationanti-inflammatoryPTMpost-translational modificationThe inflammatory response can be depicted as coordinated activation of a myriad of signaling pathways that come together to regulate the expressions of both pro- and anti-inflammatory mediators. One of the most classic pro-...
由于前列腺素(PGI2)在体内的半衰期短,可迅速讲解为6-keto-PGF1a,所以可测定肺组织中的6-keto-PGF1a浓度来反映前列腺素(PGI2)水平。 前列环素(PGI2)通过刺激环磷酸腺苷(cAMP)的生成引起肺血管平滑肌舒张并抑制平滑肌的生长,同时有强大的抗血小板聚集作用。同时,前列环素(PGI2)有抑制肺成纤维细胞合成胶原的作用。
15-PGDH Negative Control (15-keto PGE2) 供应商 Cayman Chemical 产品货号 701984-250 产品报价 ￥询价/250ul 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 产品新闻 背景资料
The 24 hour urinary excretion of 6-keto PGF1α and PGE2 was compared in 2 kidney-1 clip rats developing hypertension within 12 weeks of renal artery clipping with rats remaining normotensive over this period. Although systolic blood pressure was markedly elevated in the hypertensive (210 ± 5.1...
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Effect of acute surgical vagotomy on the mucosal content of 6-keto-PGF1 alpha, PGE2 and glutathione after intragastric 96% ethanol treatment in rats. It has been observed earlier that gastric cytoprotection produced by PGI2, beta-carotene, small doses of atropine or cimetidine has failed in surg...
目的 通过NSAIDs灌胃引起大鼠胃黏膜损伤,然后观察胃热消炎合剂对6-keto-PGF1α,PGE2表达的调控作用.方法 雄性SD大鼠36只,适应性喂养一周后随机平均分成6组:①空白对照组;②模型对照组;③阳性对照组;④低剂量组;⑤中剂量组;⑥高剂量组.给予不同处理5d后,给予损伤处理2次并处死大鼠.放免法检测胃黏膜6-keto-PGF...
目的:本课题根据中医传统理论,结合现代研究,通过复制慢性应激肝郁雌性大鼠模型,以舒肝补肾中药进行干预,分析肝郁对女性排卵功能及对血浆前列腺素E2(PGE2),6-酮前列腺素F1α(6-Keto-PGF1α),血清肿瘤坏死因子-α(TNF-α)含量的影响,再次探讨肝郁与排卵功能异常的关系及舒肝补肾中药的作用机理,对排卵功能异常的治疗提...
Plasma iPGE2 and i6-keto PGF1 alpha were measured with an EIA assay in twenty patients with alcohol-related liver cirrhosis (ALC group) and 13 patients with hepatitis B virus as an etiologic factor of liver cirrhosis (HLC group). Significant increase of both prostanoids was observed irrespective...
The time-dependent release of prostaglandin E2 (PGE2), prostaglandin F2 alpha (PGF2 alpha), thromboxane (Tx) B2, and 6-keto-PGF1 alpha (6-keto) from brain was measured before, during, and after a 15-min interval of total ischemia (four-vessel occlusion) in halothane-anesthetized cats usin...