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10. Here, ACP binds to apo-KS, upon which ACP chain-flips53 its cargo into the KS active site as KS loops 1 and 2 move in a coordinated manner to assume an open conformation, forming a transient, hydrophobic delivery/extraction pocket that temporarily accommodates the substrate (Fig. 10b...
Further attempts should be made to improve the bioavailability of AKBA through lipid based delivery systems. As the literature suggested that the intake of a high fat meal increases three to fivefold in the plasma concentrations of boswellic acid molecules [47]. In addition to the above reported...