Baker, APC (San Diego, CALIFORNIA, US) Claims: What is claimed is: 1. A recombinant, artificial, or engineered metabolic pathway, comprising: (i) conversion of pyruvate to acetyl phosphate; (ii) conversion of acetyl phosphate to acetyl-coA; (iii) a first cofactor-dependent enzyme that ...
Induction of moncyte differentiation and foam cell formation in vitro by 7-ketocholesterol. J Lipid Res 2002; 43:26-35. Hicok KC, Thomas T, Gori F, Rickard DJ, Spelsberg TC, Riggs BL. Development and characterization of conditionally immortalized osteoblast precursor cell lines from human ...
1. Marine Biology Research Division, A-002, Scripps Institution of Oceanography, University of California, San Diego, 92093, La Jolla, California, USASpringer-VerlagJournal of Comparative Physiology BWalsh PJ. Purification and characterization of two allozymic forms of octopine dehydrogenase from ...
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2-Keto-3-deoxy-6-phosphogluconate aldolase eda 2KD6PG -> T3P1 + PYR 1 Citrate synthase gltA ACCOA + OA -> COA + CIT 1 Aconitase A acnA CIT <-> ICIT 1 Aconitase B acnB CIT <-> ICIT 1 Isocitrate dehydrogenase icdA ICIT + NADP <-> CO2 + NADPH + AKG 1 ...
Reaction of lactone 4 with an alkyl lithium or Grignard reagent affords a keto alcohol and subsequent protection of the alcohol as before to afford 11. Baeyer-Villiger oxidation of the ketone function affords an acetate, alkaline hydrolysis of which serves to introduce a second alcohol function ...
9, SLex tetrasaccharides containing natural sialic acid forms including N-acetylneuraminic acid (Neu5Ac), N-glycolylneuraminic acid (Neu5Gc), 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid (Kdn), as well as 9-O-acetylated Neu5Ac and Neu5Gc were obtained in excellent (85-93%) ...
It is believed to be stabilized into the enzyme's active site through a ketoamide. See, e.g., Lin et al., 2005, J Biol Chem. Manuscript M506462200 (epublication); Summa, 2005, Curr Opin Investig Drugs. 6:831-7, the contents of which are hereby incorporated by reference in their ...
a keto thiolase can be encoded by an atoB gene, polynucleotide or homolog thereof, or an fadA gene, polynucleotide or homolog thereof. The atoB gene or fadA gene can be derived from any biologic source that provides a suitable nucleic acid sequence encoding a suitable enzyme. For example, ato...