Iwata M; Inoue S; Kawaguchi M;.Ketamine eliminates propofol pain but does not affect hemodynamics during induction with double-lumen tubes.J Anesth.2010.31-37Ketamine eliminates propofol pain but does not affect hemodynamics during induction with double-lumen tubes[J] . Masato Iwata,Satoki Inoue,...
Male C57BL6 mice aged 5–13 weeks received a single intraperitoneal injection of either vehicle (saline), (R,S)- ketamine (3 or 10 mg kg − 1), (2R,6R)-HNK (10 mg kg − 1) or pentobarbital (5 mg kg − 1). Animals were randomly injected with either saline, ketamine, (2...
Ketamine administration was associated with an increase of false alarms that was most pronounced for false alarms to BX sequences at both short and long ISI. A repeated-measures ANOVA demonstrated a significant 3-way interaction of infusion × time × false-alarm type (F4,15 = 3.33, P = ....
timeP = 0.5614, experimental groupP < 0.0001, subjectP < 0.0001; significance derived from Tukey’s multiple comparisons are marked with asterisk(s); see Supplementary Fig.4for exactPvalues).fKO-ketamine mice have
Inclusion criteria were studies (1) including healthy participants; (2) reporting symptoms occurring in response to acute administration of subanesthetic doses of ketamine (racemic ketamine, s-ketamine, r-ketamine) intravenously; (3) containing a placebo condition with a within-subject, crossover ...
0.08±0.02, P≤0.05, n=8, ondansetron vs. saline. These data provide evidence that naturally occurring differences in serotonin function alter the ECG response of the animals to ketamine and that activation of the serotonin type-3 receptor by ketamine is involved.DePetrillo...
Background: Postoperative pain is of greatest concern in parturients undergoing cesarean section. Low-dose intravenous (IV) ketamine infusion has been considered to be an effective postoperative analgesia and resurged again as a substitute of opioid analgesics. This study aims to evaluate the ...
Study designSubjectsSample sizeBiomarkersCase vs controlCorrelation between inflammatory factors and depressionReference Meta-analysis MDD vs HCs N/A Peripheral blood IL-6, TNF-α, IL-10, sIL-2R, CCL-2, IL-13, IL-18, IL-12, IL-1Ra, sTNFr2 MDD (vs HCs) ↑ Not available [20] INF-...
Level of dissociation may influence ketamine's effects in OCD. Fourth, in our study 2 of 15 subjects had comorbid depression (with baseline HDRS-17 scores of 13 and 16), and no significant differences in depression bet- ween infusion type. In contrast, in Bloch et al's trial, 7 out ...
lenti-NC; #p < 0.05 vs. lenti-over/miR-29b-3p Full size image Presynaptic terminal N-type, P/Q-type, and R-type voltage-dependent calcium channels (VDCCs) play an important role in Ca2+ influx37. The modulating effect of miR-29b-3p on VDCCs was analyzed, and the results ...