keratin, 55K type-II cytoskeletal keratin, cuticle, ultrahigh sulphur 1 Keratin, cuticle, ultrahigh sulphur 1-like Keratin, Hair, Acidic 1 keratin, hair, acidic, 1 keratin, hair, acidic, 2 keratin, hair, acidic, 4 keratin, hair, acidic, 5 keratin, hair, acidic, 6 keratin, hair, acidic...
Mutations in keratin genes cause a diverse spectrum of skin, hair and mucosal disorders. Cutaneous disorders include epidermolysis bullosa simplex, palmoplantar keratoderma, epidermolytic ichthyosis and pachyonychia congenita. Both clinical and laboratory observations confirm a major role for keratins in mai...
Keratins are important for the mechanical stability and integrity of epithelial cells and tissues. Some keratins also have regulatory functions and are involved in intracellular signaling pathways, e.g. protection from stress, wound healing, and apoptosis. This diverse group of cytoskeletal scaffolding...
Define keratin pearl. keratin pearl synonyms, keratin pearl pronunciation, keratin pearl translation, English dictionary definition of keratin pearl. a substance found in the dead outer skin and in horn, hoofs, nails, claws, etc. Not to be confused with:
They form important cytoskeletal networks in virtually all epithelial cells that are separate from the microtubule and actin networks.26 They are also the key components in epidermal appendageal structures (eg, hair, wool, horns, hooves and nails). The keratin protein structure is made up of a ...
n = 3. (j) Colon from K8+/ + , K8− / − and K8+/+ mice were subjected to high salt extraction, and the cytoskeletal fraction was analysed by SDS-PAGE and immunoblotting for FLN and K8 Cell Death and Differentiation Notch1 signaling and keratins IAK Lähdeniemi et al 990 ...
In preliminary analyses, we have found no indication that light affects the distribution of IFAP, although we have recently observed that orthovanadate treatment results in significantly increased colocalization with the cytoskeletal cross-linker plectin (Strnad et al, 2002). Taken together, the ...
K15 was first identified as a minor keratin of human epidermis, by gel electrophoresis of cytoskeletal preparations (Moll et al.1982b,c). Its sequence demonstrated its assignment to the type I keratins (Leube et al.1988). Only later its cellular distribution was recognized, and it was uncove...
et al. Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16. Nat. Commun. 8, 14174 doi: 10.1038/ ncomms14174 (2017). Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This work is ...
Previously thought to reside exclusively in the cytoplasm, the cytoskeletal protein keratin 17 (K17) has been recently identified inside the nucleus of tumor epithelial cells with a direct impact on cell proliferation and gene expression. We comment on fundamental questions raised by this new finding...