They form important cytoskeletal networks in virtually all epithelial cells that are separate from the microtubule and actin networks.26 They are also the key components in epidermal appendageal structures (eg, hair, wool, horns, hooves and nails). The keratin protein structure is made up of a ...
keratin, 55K type-II cytoskeletal keratin, cuticle, ultrahigh sulphur 1 Keratin, cuticle, ultrahigh sulphur 1-like Keratin, Hair, Acidic 1 keratin, hair, acidic, 1 keratin, hair, acidic, 2 keratin, hair, acidic, 4 keratin, hair, acidic, 5 keratin, hair, acidic, 6 keratin, hair, acidic...
Define keratin pearl. keratin pearl synonyms, keratin pearl pronunciation, keratin pearl translation, English dictionary definition of keratin pearl. a substance found in the dead outer skin and in horn, hoofs, nails, claws, etc. Not to be confused with:
Mutations in keratin genes cause a diverse spectrum of skin, hair and mucosal disorders. Cutaneous disorders include epidermolysis bullosa simplex, palmoplantar keratoderma, epidermolytic ichthyosis and pachyonychia congenita. Both clinical and laboratory observations confirm a major role for keratins in mai...
Casein kinase IαColorectal cancerFAM83HInvasionKeratin filaments form cytoskeletal networks in epithelial cells. Dynamic rearrangement of keratin filament networks is required for epithelial cells to perform cellular processes such as cell migration and polarization; however, the mechanism governing keratin ...
K15 was first identified as a minor keratin of human epidermis, by gel electrophoresis of cytoskeletal preparations (Moll et al.1982b,c). Its sequence demonstrated its assignment to the type I keratins (Leube et al.1988). Only later its cellular distribution was recognized, and it was uncove...
n = 3. (j) Colon from K8+/ + , K8− / − and K8+/+ mice were subjected to high salt extraction, and the cytoskeletal fraction was analysed by SDS-PAGE and immunoblotting for FLN and K8 Cell Death and Differentiation Notch1 signaling and keratins IAK Lähdeniemi et al 990 ...
et al. Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16. Nat. Commun. 8, 14174 doi: 10.1038/ ncomms14174 (2017). Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This work is ...
Previously thought to reside exclusively in the cytoplasm, the cytoskeletal protein keratin 17 (K17) has been recently identified inside the nucleus of tumor epithelial cells with a direct impact on cell proliferation and gene expression. We comment on fundamental questions raised by this new finding...
Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation. Exp Cell Res 1992; 202(1):132–141. CrossRef Rugg EL, McLean WH, Allison WE et al. A mutation in the mucosal keratin K4 is associated with oral white sponge nevus. Nat Genet...