Full size image To further gain mechanistic insights into the unique substrate selectivity and hydroxylation pattern of PikCH238pAcF, we solved the crystal structures of 6-bound and 4-bound PikCH238pAcF (Supplementary Fig. 53). Similar to the substrate free PikCH238pAcF structure, in both struct...
The full name of the KC certification mark is "Korea Certification Mark", also known as the national unified certification mark of South Korea. It is a certification system implemented in accordance with South Korea's "Electrical Appliances and Household Appliances Safety Management Law", and the ...
andThe Book of Wizard Parties: In Which the Wizard Shares the Secrets of Creating Enchanted Gatherings In fact, we learned a new word while reading the books —many wizards practiced Alchemy which is an ancient form of chemistry. Since all wizards seem to have a good knowledge of spells and...
Searching across the full cohort for this haplotype uncovered two additional apparently unrelated individuals with no known genealogical connection to the original kindred. All five participants with the defined haplotype were shown to share the rare variant by targeted Sanger sequencing. If this result ...
3B–C). There was also an evident shift in the relative electrophoretic mobility (Mr) from the fully post-translationally modified form (≈125 kDa) of KV2.1 toward an Mr of ≈96 kDa, suggesting a deficit in the processing of the Kcnb1G379R variant into the mature, fully post-...
hERG-NT was abundantly detected in the insoluble fraction, whereas hERG-CM protein exhibited significantly less signal in the insoluble fraction (Fig. 5A). The protein found in the insoluble fraction is nonfunctional protein that has aggregated prior to full assembly and trafficking to the cell ...
On the contrary, two steps were noticed for the deposition of neodymium on iron: a first step to form the alloy FeNd2 and a second step where the deposition of pure neodymium was observed. The overall process had an irreversible behaviour due to the alloying properties of iron....
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