KAT8-IN-1 | MedChemExpress(MCE) 英文名称: 总访问: 130 国产/进口: 进口 半年访问: 22 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 5 g; 10 g 最后更新: 2025-2-13 货号: HY-W015239 CAS 号: 605-62-9 参考报价: 550; 900 立即询价 电话咨询 ...
KAT8-IN-1,CAS:605-62-9,KAT8-IN-1 是一种赖氨酸乙酰转移酶 8 (KAT8) 抑制剂,IC50 分别为 141 μM (KAT8)、221 μM (KAT2B)、106 μM (KAT3B)。KAT8 抑制组蛋白乙酰转移酶 (HATs),可能导致疾病,如癌症或炎症。
KAT8通过p53乙酰化/NLRP3炎症小体轴调控LPS诱导急性肺损伤的机制及MG149治疗潜力 《Archives of Biochemistry and Biophysics》:Inhibition of histone acetyltransferase KAT8 inhibits oxidative stress and NLRP3 inflammasome activation through reducing p53 acetylation in LPS-induced acute lung injury 编辑推荐: 本研...
Fascin actin‐bundling protein 1 (Fascin) is highly expressed in a variety of cancers, including esophageal squamous cell carcinoma (ESCC), working as an important oncogenic protein and promoting the migration and invasion of cancer cells by bundling F‐actin to facilitate the formation of filopodia...
Immunotherapies targeting the PD-1/PD-L1 axis have become first-line treatments in multiple cancers. However, only a limited subset of individuals achieves durable benefits because of the elusive mechanisms regulating PD-1/PD-L1. Here, we report that in
At first, Using siRNA targeting 5 MYST members for functional screening, the authors found that deficiency in KAT8 selectively promotes the production of IFN-I. The data showed that KAT8 selectively inhibited IFN-1 production in macrophages and DCS induced by RNA and DNA virus infection. Then,...
Pancreatic cancer (PC) remains one of the most lethal malignancies with unfavorable prognosis globally. Bioinformatics analysis predicted that SEPP1 was low expressed in PC and related to tumor immune microenvironment, but its biological function was sti
To investigate the function of KAT8 in placentation, we generatedKat8f/ftransgenic mouse model by inserting Loxp fragments into exons 2 and 3 of theKat8gene (Fig.1b; Supplemental Fig.1a). Subsequently, we crossedKat8f/fwithElf5-Cremice, which specifically function in trophoblasts29, to ...
Chat Live|Log in|Join Free||| Add to Favirate|HomePage Products Buying Leads Chemical site Hot Keywords:18162-48-6,872-50-4,Methylene Chloride,naphthalene,THF,Titanium Dioxide KAT8/MYST1 antibody (PE) Basic informationMore.. Product Name:KAT8/MYST1 antibody (PE) ...
(G and H) Foci formation ability was assessed after KAT8 knockdown or knockout; data represent statistical analysis of colony number in below panel. (I–K) KYSE30 cells stably infected with lentivirus (scramble, shKAT8-1#, and shKAT8-2#) were subcutaneously injected into the flank of NU...