【翻译】急性髓系白血病伴t(8;16)(p11.2;p13.3);KAT6A-CREBBP多为治疗相关,常有(原幼细胞)吞噬红细胞现象,通常表现为粒-单核细胞或单核细胞特征。 【翻译】急性髓系白血病伴t(8;16)(p11.2;p13.3);KAT6A-CREBBP 该病种...
t(8;16)(p11.2;p13.3)/KAT6A-CREBBP is a rare recurrent cytogenetic abnormality associated with acute myeloid leukemia (AML). We report 15 cases with t(8;16)(p11.2;p13.3). All patients were adult and had AML: 13 women and 2 men, with a median age of 50 years. Ten patients had a...
本期专家门诊为您带来一例重症儿童抗生素相关性腹泻病的治疗经验分享。抗生素相关性腹泻(antibiotic-associateddiarrhea,AAD)是指应在抗生素应用过程中或是停用抗生素2个月后引起的不能用其他原因解释的腹泻。约有13%~24%的患者在抗生素使用的4周内发病。约15%~25%的病原菌为艰难梭菌,其他致病菌包括产气荚膜菌、金...
KAT6A and KAT6B proteins stimulate cancer cell growth by influencing the cell cycle. For this reason, inhibiting their action can stop malignancy and put it into a completely dormant state without destroying its cells. However, before such a drug is developed, a number of studies should be con...
记忆是个体对于事物特征及事件过程的记识,保持以及再认或回忆的过程,长时记忆是保持时间相对持久的记忆类型之一.EP300,CREBBP和PCAF是KAT家族中重要的组蛋白乙酰化转移酶.以往研究发现这三个酶可单独,或通过形成复合物调节多个与长时记忆相关基因的表达.Ep300,Crebbp和Pcaf敲除模...