kappa/lambda ratio sTLC: serum total light chain sFLC: serum free light chain ROC: Receiver operating characteristic AUC: area under the curve SPE: serum protein electrophoresis sIFE: serum immunofixation electrophoresis MGUS: monoclonal gammopathy of undetermined significance AL: Immunoglobuli...
The ratio of kappa to lambda chains in urine was 0.178, much less than the ratio in serum (1.3). Six other urine samples from a group of patients with documented Bence Jones proteinuria also exhibited kappa/lambda ratios that differed manyfold from the ratios in their corresponding serum ...
The shorter survival of lambda-LCD patients could not be ascribed to an increased incidence of recognized manifestations indicating a poor prognosis (e.g., anemia, hypercalcemia, azotemia, low albumin, the extent of osteolytic lesions, or proteinuria), the incidence of amyloidosis, the clinical ...
Ratio FLC value (kappa FLC/lambda FLC) compared to reference ranges may indicate presence of plasma cell disorders disease like Multiple Myeloma or AL amyloidosis in a patient. Nephelometric and turbidimetric based assays have been shown to overestimate the sFLC levels that are not always consistent...
, kappa/lambda ratio, + and CD8+ subpopulations were studied in patients with (SMM), active (MM) and (). The l... G Büchi,M Girotto,M Veglio,... - 《Haematologica》 被引量: 7发表: 1990年 Treatment of AL amyloidosis Free light chainsHaematologic responseAL amyloidosis is caused by ...
The 99% confidence limits of controls were calculated for kappa, lambda, and the ratio of both light chains.J van SteijnJ. BijzetH. de WitB.P.C. HazenbergI.I. van GamerenK. van de BeltVellengAmyloid and amyloidosis
Free kappa and lambda light chains in fat tissue supernatants were quantified with a nephelometric immunoassay (FreeLite~(TM)) with specific antibodies against hidden epitopes (1). The 95% confidence limits of controls were calculated for kappa, lambda, and the ratio of both light chains. Congo...