Rapid Multi-Drug 2-12 Test is a rapid, screening test for the qualitative detection of multiple drugs and drug metabolites in human urine at specified cut off levels.Detection time: Within 3-4 days in urine. Contents: IFU Test cassette Desiccant Cut off level: Drug name...
This relieves PTCH1 repression on the seven-pass transmem- brane protein Smoothened (SMO) and enables SMO to translocate to the cilium tip, driving a signaling cascade that culminates in the production of glioma-associated oncogene (GLI) activators. There are three GLI zinc finger tran- script...
of the drug effect between genotypes on days 1 and 7 by unpaired Student's t-test. (e) Apomorphine-induced vertical activity in control and D2RcreGrk2f/f mice (n ¼ 10–12 mice for each group). *po0.05, comparison of the drug effect between genotypes by unpaired Student's t-test....
Polona nidari-Plazl,I Plazl - 《Lab on A Chip》 被引量: 122发表: 2007年 High-throughput mapping of brain-wide activity in awake and drug-responsive vertebrates The reconstruction of neural activity across complete neural circuits, or brain activity mapping, has great potential in both fundame...
Furthermore, we investigated the role of GRK2 inhibition (using GRK2f/fLyz2-Cre+/− mice) on MDMs of collagen-induced arthritis (CIA) mouse model. Mechanistically, we identified GRK2-interacting protein and downstream signaling by RNA-seq and dual-luciferase reporter. Our results provide a ...
The Mouse Light–Dark Box Test The light/dark test is based on the innate aversion of rodents to brightly illuminated areas and on the spontaneous exploratory behaviour of the animals, a... Martine Hascot,M Bourin - Humana Press 被引量: 1020发表: 0年 Locally Decodable Codes with Two Querie...
One Step Test Drug of Abuse Test Item Cat.No. Format Specimen Cut-off Certification Morphine (MOP/MOR) BMOP02C-1/2 Strip/Cassette Urine 300ng/mL CE Methamphetamine (MET) BMET02C-1/2 Strip/Cassette Urine 1000ng/mL CE Ketamine (KET) BKET02C-1/2 Strip/Cassette Urine 500/...
On the alcohol- and water-catalyzed tautomerization of vitamins K1- and K2-derived quinone methide intermediates. Rates of conversion of 1,3-methides into the corresponding 1,2-methide tautomers, formed upon laser-excitation of vitamins K(1) and K(2) in CH(3)CN solutio... AM Swartz,Moni...
1G), which is consistent with the reversed effect of IBMX on cytosolic calcium in siGRK2 cells (Fig. 1E). Interestingly, the reduction in glucose-mediated calcium signal is rescued by PTx, a Gαi/o inhibitor, suggesting that reduction of GRK2 promotes Gαi/o-inhibitory pathways (Fig. ...
The test article was weighed on an electronic balance (BCE2202I-1SKR, Sartorius, Germany). Afterwards, the MCT oil was added to prepare the article into the stipulated concentrations. The homogeneity of the prepared articles and stability (room temperature: 7 days) of the low (4 mg/mL) and...