This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Four ...
DefinitionDefinitionJNK; Is a subfamily of mitogen-activated protein kinases (MAPKs) primarily activated in response to environmental stresses and proinflammatory cytokines. JNKs phosphorylate two regSpringer Berlin HeidelbergJun N-terminal kinase. Circ Res 99: 1004-1011, 2006....
英文名称 Rat c-Jun N-terminal kinases, JNK Elisa Kit 规格 96T/48T 包装 盒装液体 贮藏 2-8℃,避光防潮保存 运输方式 顺丰快递 使用方法 竞争法、夹心法、间接法 样本类型 血清,血浆,尿液,组织匀浆等 用途范围 仅用于科研 特点 特异性强,重复性好 运输 免费包邮 有效期 6个月 发货地 ...
c-Jun N-terminal kinases ELISA Kit 更多供应商 上海雅吉生物科技有限公司 联系电话: 021-34661275 15301693058 产品介绍: 中文名称:人c-Jun氨基末端激酶(JNK)ELISA试剂盒 纯度:99% 备注:1盒/RMB 1200 坛墨质检科技股份有限公司 联系电话: 4008-099-669 产品介绍: 中文名称:人c-Jun氨基末端激酶(JNK)...
英文名称: c-Jun N-terminal kinases/JNK kit 用途: 用于科研实验,不得用于临床 产地: 上海 品牌: 梵态生物 包装规格: 96T 1800元/48T 1200元 标记物: 咨询客服 样本: 血清,血浆,细胞,组织,等相关液体 检测方法: 酶联免疫法 应用: 定量/定性/酶活检测 检测限: 咨询客服 货号: FT-P3110...
英文全称:c-Jun N-terminal kinases 检测范围:0.75ng/mL~24ng/mL 灵敏度:0.1 货号:FS10106 试剂盒组成及试剂配制 : 1. 酶联板(Assay plate ):一块(96孔)。 2. 标准品(Standard):2瓶(冻干品)。 3. 样品稀释液(Sample Diluent):1×20ml/瓶。
Thrombin activates two stress-activated protein kinases, c-Jun N-terminal kinase and p38, in HepG2 cells Hepatology, 27 (1998), pp. 1362-1367 Google Scholar 34. K.L. Gould, J.R. Woodgett, J.A. Cooper, et al. Protein kinase C phosphorylates pp60src at a novel site Cell, 42 (1985...
The c-Jun N-terminal kinases consist of ten isoforms derived from three genes: JNK1(four isoforms), JNK2 (four isoforms) and JNK3 (two isoforms).[2] Each gene is expressed as either 46 kDa or 55 kDa protein kinases, depending upon how the 3' coding region of the corresponding mRNA ...
The activation of c-Jun N-terminal kinases (JNKs) plays an important role in physiological processes including neuronal function, immune activity, and development, and thus, JNKs have been a therapeutic target for various diseases such as neurodegenerative diseases, inflammation, and cancer. Efforts...
play a role in T cell differentiation and the cellular apoptosis pathway.Activation occurs through a dual phosphorylation of threonine (Thr)and tyrosine (Tyr) residues within a Thr-Pro-Tyr motif located in kinase subdomain VIII. Activation is carried out by two MAP kinases,MKK4 and MKK7 and ...