Doublecortin JNK Subfamily MAP-KinasesBalazs RadnaiCsenge AntusBoglarka RaczPeter EngelmannJanos K PriberZsuzsanna TucsekBalazs VeresZsuzsanna TuriTamas LorandBalazs SumegiSpringer Berlin HeidelbergJNK, c-Jun N-terminal kinase; OPG, osteoprotegerin; TRAP, tartrate-resistant acid...
c-Jun N-Terminal Kinases (JNK1, JNK2, and JNK3) JNK was initially discovered by its ability to phosphorylate the N-terminal transactivating domain of the transcription factor c-Jun. As its activity was stimulated primarily by cellular stress rather than by mitogens, contrary to ERKs, it was...
JNK include c-Jun, ATF2, ELK1, SMAD4, p53 and HSF1. JNKs can associate with scaffold proteins JNK interacting proteins as well as their upstream kinases JNKK1 and JNKK2 following their activation. JNK activity regulates several important cellular functions including cell growth, differentiation, ...
The c-Jun amino-terminal kinase (JNK) group of MAP kinases has been identified in mammals and insects. JNK is activated by exposure of cells to cytokines o... YT Ip,RJ Davis - 《Current Opinion in Cell Biology》 被引量: 786发表: 1998年 Zhuang ZY, Wen YR, Zhang DR, Borsello T, ...
6)c-Jun amino-terminal kinasec-Jun 氨基末端激酶 1.Expression of α-smooth muscle actin(α-SMA),secretion of fibronectin (FN)andc-Jun amino-terminal kinase(JNK)activity were assayed by Western blot and ELISA,the change of distribu- tion of α-SMA in mesangial cells before and after IL-1...
c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling C. A. Escudero, C. Cabeza, G. Moya-Alvarado, M. T. Maloney, C. M. Flores, C. Wu, F. A. Court, ...
c-Jun N-terminal kinase (JNK) is a universal and essential subgroup of the mitogen-activated protein kinase (MAPK) superfamily, which is highly conserved from yeast to mammals and functions in a variety of physiological and pathological processes. In this study, we report the first oyster JNK ...
4.Role of c-Jun N-terminal kinases in injury of hippocampus in rats exposed to chronic hypoxic hypercapniac-Jun氨基末端激酶在慢性低O_2高CO_2大鼠海马损伤中的作用 5.Function and relationship between c-Jun N-terminal kinase and caspase in apoptosisc-Jun氨基末端激酶与caspase在细胞凋亡中的作用及相...
Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9, 576–596 (1995). 44. Ip, Y. T. & Davis, R. J. Signal transduction by the c-Jun N-terminal kinase (JNK)—from inflammation to development. Curr. Opin. Cell...
Laboratory Investigation (2009) 89, 470–484 & 2009 USCAP, Inc All rights reserved 0023-6837/09 $32.00 Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat Frank Y Ma1,3, Robert S Flanc1,3, Greg H Tesch1, ...