Probes for Mitochondria—Section 12.2 引用和文献(400) Apoptosis induced by Rac GTPase correlates with induction of FasL and ceramides production. Authors:Embade N,Valerón PF,Aznar S,López-Collazo E,Lacal JC Journal:Molecular biology of the cell ...
ART targeting to mitochondria also significantly improved its efficacy, but the effect of ART on mitophagy, an important cellular pathway that ... More Ziram, a dithiocarbamate fungicide, exhibits pseudo-cytoprotective actions against oxidative stress in rat thymocytes: Possible environmental risks. ...
Mitochondria-targeting supra-carbon dots: Enhanced photothermal therapy selective to cancer cells and their hyperthermia molecular actionsCarbon 2020 (IF=8.821) 2.Tengjie Li, et al. Novel antifungal mechanism of oligochitosan by triggering apoptosis through a metacaspase-dependent mitochondrial pathway in ...
JC-1 has advantages over other cationic dyes in that it enters the mitochondria and changes its fluorescent properties based on the aggregation of the probe. In healthy cells with high ΔΨM, JC-1 forms complexes known as J-aggregates with intense red fluorescence. However, in cells with ...
For most cells, the membrane potential of the mitochondria will be completely lost after 20 minutes of treatment with 10μM CCCP. After staining with JC-1, it should show green fluorescence; while normal cells should show red fluorescence after staining with JC-1. For specific cells, the ...
JC-1 has advantages over other cationic dyes in that it enters the mitochondria and changes its fluorescent properties based on the aggregation of the probe. In healthy cells with high ΔψM, JC-1 forms complexes known as J-aggregates with intense red fluorescence. However, in cells with ...
JC-1 mitochondrial membrane potential assay is a fluorescence-based method to track the behavior of mitochondria. Mitochondrial membrane potential (MMP) is an important parameter of mitochondrial function that has been used as an indicator of cell apoptosis. Several cell membrane permeable fluorescent dy...
规格或纯度 A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential δΨm in cells, tissues, and isolated mitochondria. 英文名称 JC-1 生化机理 主要靶标用作细胞,组织和分离的线粒体中线粒体电位δΨm的比率指示剂产物不与ATP竞争。可逆:否细...
图片及说明 Fig. Hela cells stained with Abbkine Mitochondrial Membrane Potential Assay Kit (JC-1). A: Red fluorescence indicates healthy mitochondria, B: Green fluorescence indicates mitochondria in poor health (30min incubation in 20uM CCCP).相关...
JC-1 (CBIC2) 是一种荧光亲脂性羰花青染料,用于测量线粒体膜电位。线粒体膜电位较高时,它在基质中汇聚形成聚合物,可以产生红色荧光(λex=585 nm,λem=590 nm)。线粒体膜电位较低时,它不能聚集在线粒体基质中,以单体形式存在产生绿色荧光(λex=510 nm,λem=527 nm)。