本报告分享一位31岁男性患者的成功案例,他患有FLT3-TKD突变的MPAL,在经历了针对性化疗、吉瑞替尼治疗及两次脐带血移植后实现了长期无病生存。 患者经JALSG ALL202-O化疗方案及吉瑞替尼靶向治疗后,迅速达到了血液学缓解。随后,患者接受了脐带血移植,术后面临腺病毒诱发的出血性膀胱炎,通过及时的膀胱冲洗和抗病毒药...
Recently, as protocols for pediatric ALL are used for young adult ALL, HD-MTX therapy is used for adult ALL in some protocols; however, its effectiveness for adult ALL has not been confirmed in a rigorous manner. Here, Japan Adult Leukemia Study Group (JALSG) conducted a randomized phase ...