本报告分享一位31岁男性患者的成功案例,他患有FLT3-TKD突变的MPAL,在经历了针对性化疗、吉瑞替尼治疗及两次脐带血移植后实现了长期无病生存。 患者经JALSG ALL202-O化疗方案及吉瑞替尼靶向治疗后,迅速达到了血液学缓解。随后,患者接受了脐带血移植,术后面临腺病毒诱发的出血性膀胱炎,通过及时的膀胱冲洗和抗病毒药...
Effectiveness of High-Dose MTX Therapy for Adult Ph-Negative ALL By Randomized Trial: JALSG ALL202-OThe effectiveness of high-dose (HD) methotrexate (MTX) therapy was confirmed in pediatric acute lymphoblastic leukemia (ALL) by randomized control studies. Recently, as protocols for pediatric ALL ...