这项分析的本质类似于构建预测模型时所使用的经典统计迭代法,通过逐个剔除SNP来判断某个SNP是否对结果造成显著改变。 默认采用的是反方向加权方法(inverse variance weighted method),只需观察"All"的值是否大于0即可,若大于0则表示结果可靠,重点关注中心点的位置。 值得注意的是,在文献中,作者并未采用常规的敏感性分...
在《Doing Meta-Analysis in R: A Hands-on Guide》中,作者提到: This method is the most common approach to calculate average effects in meta-analyses. Because we use the inverse of the variance, it is often calledinverse-variance weightingor simplyinverse-variance meta-analysis. 如何在R中实现呢?
1.Burgess S, Thompson SG.Interpreting findings from Mendelian randomization using the MR-Egger method.Eur J Epidemiol. 2017 May;32(5):377-389. doi: 10.1007/s10654-017-0255-x. Epub2017 May 19.
Jessica Rees, Angela Wood, Stephen Burgess. Extending the MR?Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy. Statistics in Medicine 2017; 36(29): 4705-4718. doi: 10.1002/sim.7492. 2.2 egg...
Disclosed are a video processing method and system, intelligent video management platform (IVM) and intelligent video processing unit (IVU), the system comprising the IVM and the IVU; the IVW is used to store and manage the capability set of administered IVUs, and according to the request of...
只需要使用method_list参数指定即可，就像下面这样： # 指定其他方法 result_add_method <- mr(...
windowClosing Method Detail init void init(VWSessionInfo sessionInfo) Retrieves the necessary session information to initialize the application. Parameters: sessionInfo - A VWSessionInfo object that contains the session-related information necessary to initialize this applic...
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If you use this software please consider citing the original multi-SNP-based SMR method and software: Wu Y, Zeng J, Zhang F, Zhu Z, Qi T, Zheng Z, Lloyd-Jones LR, Marioni RE, Martin NG, Montgomery GW, Deary IJ, Wray NR, Visscher PM, McRae AF & Yang J (2018) Integrative analys...
192 kHz 384 kHz VOS DNR Output offset voltage Dynamic range A-Weighted, -60 dBFS Method -1 109 1 mV dB SNR Signal to noise ratio A-Weighted, Referenced to 1 % THD+N Output Level 112.5 dB KCP Click and pop performance Into and out of Mute, Shutdown, Power Up, Power Down and audio...