Ischemic preconditioning in the rat brain enhances the repair of endogenous oxidative DNA damage by activating the base-excision repair pathway. The development of ischemic tolerance in the brain, whereby a brief period of sublethal ‘preconditioning’ ischemia attenuates injury from subsequent seve... ...
Because stroke is essentially a disease of the vessels and blood flow, the most fundamental aspects of ischemic blood flow in the brain are under investigation by researchers. Their work was the focus of the sixth in the series of Keio University International Symposia for Life Sciences and Medic...
aThe brain is particularly vulnerable to ischemic insult because of the high metabolic rate, relatively low oxygen stores, and insufficient reserves of high-energy carbohydrates, which usually results in neurological dysfunction. 脑子是特别脆弱的到局部缺血的侮辱由于高能碳水化合物高新陈代谢率、相对地低含...
Some kinds of drugs for prevention and treatment ofischemic strokeare introduced in this review. 本文介绍防治缺血性脑卒中的几类主要药物. 互联网 展开全部 英英释义 Noun 1. the most common kind of stroke; caused by an interruption in the flow of blood to the brain (as from a clot blocking ...
on current data that support a pathogenic role of ROS originating from mitochondrial respiratory chain in the promotion of secondary energy failure and proposes potential therapeutic strategy against reperfusion-driven oxidative stress following hypoxia-ischemia-reperfusion injury of the developing brain. ...
摘要: Ischemic injury, inflammation and repair in the heart : inflammation and repair in the lung : inflammation and repair in the brain (PreTest key concepts, 4) McGraw-Hill, c1995出版时间: 1995 ISBN: 0070520062 收藏 引用 批量引用 报错 分享 ...
We have tested whether small intraischemic variations in brain temperature influence the outcome of transient ischemia. To measure brain temperature, a thermocouple probe was placed stereotaxically into the left dorsolateral striatum of rats prior to 20 min of four-vessel occlusion. Rectal temperature ...
Apoptosis may contribute to a significant proportion of neuron death following acute brain ischemia (ABI), but the underlying mechanisms are still not fully understood. Brain ischemia may lead to stroke, which is one of the main causes of long-term morbidity and mortality in both developedand dev...
BACKGROUND Hypoxic-ischemic brain injury in the perinatal period is a main cause of perinatal mortality and neurologic complications in neonates and children. Recent studies have focused on the neuroprotective effect of anesthetic drugs... Jia-Shui,Yu-Fen,Wang,... - 《Medical Science Monitor Intern...
This article reviews the currently available experimental methods to induce ischemic tolerance in the brain and gives a brief summary of the potential mode of action.doi:10.1556/APhysiol.92.2005.1.9Chen, J.Simon, R.NeurologyChen J,Simon R.Ischemic tolerance in the brain. Neurology . 1997...