ischemic brain injury suggest the commonest lesion is wide- spread WM gliosis (3,6). Placental abruption is an identified antecedent factor (7). Regional differences in vulnerability to HI exist (8,9). Pre- term WM is susceptible to HI, and inflammation due to the selective vulnerability ...
Results from a gerbil animal model study indicated that a high-fat diet accelerates and exacerbates microgliosis and neuronal damage [33]. Although extra virgin olive oil (EVOO) or other oils rich in monounsaturated fat have been reported to bring some benefits to the cardiocerebral vascular ...
function of Nrf2 mice, the authors have observed that pre-treatment with DMF for 7 days prior to hypoxia-ischemia confers robust and prolonged Nrf2-dependent neuroprotection by involving anti-oxidative and anti-inflammatory response and the attenuation of reactive gliosis in astrocyte and microglia. ...