VLDL or LDL cholesterol: which is more atherogenic?doi:10.1016/S0021-9150(00)80712-1StephenG. YoungElsevier Ireland LtdAtherosclerosis
Thus, a large portion of the CHD risk conferred by LDL may be attributable to LDL that contains apoC‐III. Very‐low‐density lipoprotein (VLDL) and LDL with apoC‐III have varying amounts of apoE. We hypothesized that a high content of apoE lessens the adverse influence of apoC‐III on...
Results indicate: (1) mouse hepatocytes respond to insulin by reducing VLDL apo B output; (2) both VLDL B100 and B48 secretion are suppressed; and (3) insulin inhibition of VLDL apo B secretion is retained in Ldlr-/- hepatocytes. 展开 关键词: Insulin VLDL LDL Apo B B100 B48 LDL ...
Increased VLDLs and the accompanying hypertriglyceridemia underlie the synthesis of small, dense LDLs with lower affinity for the LDL receptor. Oxidized LDLs could bind scavenger receptors and promote an inflammatory response. An overexpression of inflammatory cytokines could activate cholesterol synthesis ...
respectively. The study showed that the MetS group had a significantly lower mean total DASH score than the control group (23.13 ± 5.44 vs. 24.62 ± 5.07,p= 0.0023). In addition, it was found that an increase in the total DASH score was associated with a lower risk of MetS (odds rati...
Background: Metabolic syndrome (Met-S) is considered one of the most important health problems of the 21st century. It includes a group of metabolic disorders that increase the risk of cardiovascular diseases such as overweight and obesity, elevated lipi
When fructose get turned into fat in the liver, it is shipped out as VLDL cholesterol particles. However, not all of the fat gets out, some of it can lodge in the liver. This can lead toNon-Alcoholic Fatty Liver Disease(NAFLD), a growing problem in Western countries that is strongly as...
and stored at −80 °C. Measurements for total-cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, VLDL, AST, ALT and creatinine were obtained from serum samples using enzymatic assays. HbA1c was measured using a turbidemetric assay in whole-blood samples (Roche Diagnostics). All ...
(low-density lipoprotein or LDL), and the “baddest” of the bad, small low-density lipoproteins (sLDL). Every 1% elevation of cholesterol confers a 2% increase in early mortality. Total cholesterol includes...
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