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ALS genetic epidemiology 'How simplex is the genetic epidemiology of ALS?'. J Neurol Neurosurg Psychiatry 2017:jnnp-2016-315469 (published Online First: 2017/02/18).Veldink JH. ALS genetic epidemiology 'How simplex is the genetic epidemiology of ALS?'. Journal of Neurology, Neurosurgery & ...
A meta-analysis found maternal PCOS increases the odds of an autism diagnosis in their children by 66% (Katsigianni et al., 2019), an effect which appears to be independent from genetic factors related to PCOS (Cesta et al., 2020). However children of women with PCOS are also at ...
There is a regulatory approval bottleneck in the translation of the latest advances in precision cancer therapies to patients1. This has led to patients’ perception, perhaps unfairly, that regulators are unnecessarily delaying access to life saving therapies2. It is critical that regulatory frameworks...
Age and sex are major risk factors in Alzheimer’s disease (AD) with a higher incidence of the disease in females. Neuroinflammation, which is a hallmark of AD, contributes to disease pathogenesis and is inexorably linked with inappropriate microglial ac
(2017) dismissed the hypothesis that chronic exposure to β-N-methylamino-L-alanine (BMAA) may be a risk factor for progressive neurodegenerative disease. They question the growing scientific literature that suggests the following: (1) BMAA exposure causes ALS/PDC among the indigenous Chamorro ...
75 days for a serval and 65 days for a domestic cat. There are also genetic differences between the sex chromosomes of the two species. Many pregnancies are aborted or absorbed, or kittens are born prematurely. Servals can be very picky when it comes to choosing mates and often will not ...
But scientists soon realized that genetic maps were less like an instruction manual and more like the parts catalog you get with Ikea furniture. What’s more, researchers discovered other catalogs that added complex variables to the relationships between genes and disease—for example, the proteome,...
16. How rapidly shark populations are able to evolve to counteract the mounting ecological threats that face them and rebound from historically low population densities will ultimately be dependent on the genetic diversity within populations, a value that itself is dependent on the germline mutation ...
A photoreceptor cell line, 661W, derived from a mouse retinal tumor that expresses several markers of cone photoreceptor cells has been described earlier. However, these cells can be differentiated into neuronal cells. Here, we report that this cell line expressed certain markers specific to retinal...