The intrinsic network of miRNAs expressed in nervous system and genes associated with ALS may provide rapid and effective outcome for therapeutic applications and diagnosis.doi:10.1155/2013/383024Santosh ShindeNeelima AroraUtpal BhadraHindawiInternational Journal of Plant Genomics...
Among them, SOD1, FUS and TARDBP are ranked as the three most common genes associated with ALS. However, no mutation analysis has been reported in central-southern China. In this study, we sequenced SOD1, FUS and TARDBP in a central-southern Chinese cohort of 173 patients with ALS (15 ...
The epidemiology of ALS: a conspiracy of genes, environment and time. Nature Rev. Neurol. 9, 617–628 (2013). Article CAS Google Scholar Rosen, D. R. et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59–62 (1993...
Frontotemporal lobar degeneration (FTLD) is characterized by the degeneration of neurons in the frontal and temporal lobes, and consists of a spectrum with ALS. Fusion protein nucleophosmin-human myeloid leukemia factor 1 (NPM-hMLF1), which is associated with the pathologies of myelodysplastic ...
Genes associated with sex, the extracellular matrix, the immune system, and stress responses are prominent within the "DE prior." In a series of control... M Crow,N Lim,S Ballouz,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 0发表:...
Plants were regenerated from AlSSTcms () tissue cultures grown on control med... PF Umbeck,BG Gengenbach - 《Crop Science》 被引量: 588发表: 1983年 The maize cytochrome c oxidase subunit I gene: sequence, expression and rearrangement in cytoplasmic male sterile plants The single copy of ...
Genetics. The elusive ALS genes. In amyotrophic lateral sclerosis, motor neuron death causes irreversible wasting of skeletal muscles but the genetics associated with the etiology is still... Ken,Garber - 《Science》 被引量: 41发表: 2008年 ...
Increased levels of transcripts with a longer 5′ UTR first exon of four different genes (Cd44, Lgals9, Spp1, and Clu) were also verified by RT-qPCR (Figure 5E). Notably, the use of alternative TSSs was often accompanied by increased nucleosome occupancy of the NDR of the corresponding ...
Gene ontology analysis showed number of DEGs involved in apoplast were downregulated in tolerant treated vs sensitive treated genotypes whereas cell division, binding & catalytic GO terms were up regulated (Fig.6). Cytochrome P450 enzymes which are associated with oxidative metabolism of various exogenou...
genes associated with LINE-1 andAlumethylation signatures in the heterogeneous ASD (prange: 0.00495–3.33E-26, 2274 genes) and ASD withCHD8variants (prange: 0.0258–0.000117, 302 genes) as shown in Supplementary TablesS1andS2. The categories ASD and intellectual disability were exclusively ...