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However, not only the epidemiology of liver cancer has changed. The treatment options for HCC have also evolved since the last Lancet review four years ago. "For a long time, there were only a few therapeutic options for patients with advanced tumor stages," explains PD Dr. Saborowski. In ...
The SIR for all cancers in the systemic sclerosis cohort was 1.5 (95% CI 1.2-1.9). The SIR for lung cancer was the highest (SIR 4.9, 95% CI 2.8-8.1), followed by non-melanoma skin cancer (SIR 4.2, 95% CI 1.4-9.8) and primary liver cancer (SIR 3.3, 95% CI 1.1-7.6). A ...
- 《Cancer Biology & Therapy》 被引量: 74发表: 2007年 Reactivity pattern and cytokine profile of T cells primed by myelin peptides in multiple sclerosis and healthy individuals. Autoreactive T cells specific for candidate myelin antigens, including myelin basic protein (MBP) and proteolipid ...
C Armon,LM Nelson - 《Amyotrophic Lateral Sclerosis》 被引量: 45发表: 2012年 State of the epidemiological evidence on physical activity and cancer prevention. Physical activity is a modifiable lifestyle risk factor that has the potential to reduce the risk of most major cancer sites. We examine...
Moreover, indoxyl sulfate in cerebrospinal fluid has been shown to be elevated in patients with multiple sclerosis, to positively correlate with markers of neurodegeneration, and to be reduced after disease-modifying (dimethyl fumarate) therapy47. Diet plays a crucial role in indoxyl sulfate ...
sTREM2 can be detected in blood and cerebrospinal fluid and is significantly associated with disease severity in neurological diseases, e.g., multiple sclerosis [20] and Alzheimer’s disease [21]. Despite the critical role of sTREM2 in neurologic disease, its role as a biomarker in malignancies...
MRIs can be done on different parts of your body. Brain MRI An MRI of the brain and spinal cord can help find many things, like: Blood vessel damage, including an aneurysm (a bulging or weakened blood vessel in the brain) Brain injury Cancer Multiple sclerosis (MS) Spinal cord injuries...
A role for MCs has been documented in many allergies or other mild or severe immune disorders such as psoriasis, ath- erosclerosis, rheumatoid arthritis, gastritis, as well as haemangioma, neoplasms and tumorigenesis [4–8, 100, 110–148]. It is possible that the initiation of other neu- ...
Involvement of IFN-γ and perforin, but not Fas/FasL interactions in regulatory T cell-mediated suppression of experimental autoimmune encephalomyelitis Autoaggressive, myelin-reactive T cells are involved in multiple sclerosis and its prototype experimental autoimmune encephalomyelitis (EAE) in mice. A pe...