To the best of our knowledge, this study provides the first ML model for predicting druggability of genes for PROTAC-based therapeutics. PROTACs are bifunctional molecules with two heads: one head binds to the target protein and the other one binds to E3 ubiquitin ligase, a cellular enzyme21....
Open Way01: OPC (One Point Cut); Open Way02: Cbr (Colour Break Ring); Open Way03: Score Ring; Color: Clear, Amber; Capacity: 1-25ml; Water Resistance: Type I; Acid Resistance: Type I; Alkali Resistance: Type II; Coe: 5.0 or 7.0; Glass Type: Type ...
Peak Season Lead Time: one month Product Attributes Specification Material:Food Grade Silicone+PP; Shape:High Bottle; Product Name:Silicone Travel Bottle; Size:91*54*38mm / 118*54*38mm; Weight:25g / 20g; Color:Mulitcolor or Customized; ...
One gram of each tissue was homogenized in 9 ml of PBS in gentleMACS M tubes using the appropriate setting on the gentleMACS dissociator (Miltenyi Biotec). Homogenates were filtered through 40-μm-pore-size filters and an aliquot was used to determine viable counts. The remaining homogenate ...
pittii. The isolates were also predominantly susceptible to minocycline [19/20 isolates; one isolate MIC > 8 μg/ml, resistant (R)], and the aminoglycosides amikacin (19/20 isolates; one isolate MIC = 32 μg/ml, I) and tobramycin (19/20 isolates; one isolate MIC > 8 μg/ml, R)....
Biofilm was detected for one strain at a 48 h time point, on a fibrinogen-coated surface; however, it is not known whether this clinical isolate forms biofilm on abiotic surface, whether it expresses the truncated or full-length Scl1.3 protein, and whether it produces an unknown fibrinogen-...
All stock solutions of labeled PAPs (MPAPs) and labeled FTOHs (MFTOHs) were bought separately at 50 µg/mL in methanol and used to prepare one working solution mixture for each compound class at 31.25 ng/mL or 200 ng/mL, respectively. Six-point calibration curves were prepared for each...
to that happiness to the basic problem to the bathroom to the best of one s to the convenience of to the crowd to the final consumer to the former to the full fullest to the heart and mind to the kuomintang to the last breath to the last day to the lonely little to the marrow of...
Peak Season Lead Time: one monthOff Season Lead Time: within 15 workdays Peak Season Lead Time: one month Product Attributes Specification Material:Plastic; MOQ:5000 PCS; Service:OEM & ODM; Delivery Time:15-20 Days; Usage:Cosmetics, Personal Care Product; ...
Average Lead Time Off Season Lead Time: within 15 workdaysPeak Season Lead Time: one month - Off Season Lead Time: within 15 workdaysPeak Season Lead Time: within 15 workdays Off Season Lead Time: within 15 workdaysPeak Season Lead Time: within 15 workdays ...