To the best of our knowledge, this study provides the first ML model for predicting druggability of genes for PROTAC-based therapeutics. PROTACs are bifunctional molecules with two heads: one head binds to the target protein and the other one binds to E3 ubiquitin ligase, a cellular enzyme21....
Open Way01: OPC (One Point Cut); Open Way02: Cbr (Colour Break Ring); Open Way03: Score Ring; Color: Clear, Amber; Capacity: 1-25ml; Water Resistance: Type I; Acid Resistance: Type I; Alkali Resistance: Type II; Coe: 5.0 or 7.0; Glass Type: Type ...
Peak Season Lead Time: one month---Off Season Lead Time: within 15 workdays Peak Season Lead Time: within 15 workdays Product Attributes Specification Type:Medical Imaging Consumables; Material:Plastic; Ethylene Oxide Sterilization:Ethylene Oxi...
Auranofin (AF), a gold (I)-containing phosphine compound, is being investigated for oncological application as a repurposed drug. We show here that 4~5 µM AF induces paraptosis, a non-apoptotic cell death mode characterized by dilation of the endop
pittii. The isolates were also predominantly susceptible to minocycline [19/20 isolates; one isolate MIC > 8 μg/ml, resistant (R)], and the aminoglycosides amikacin (19/20 isolates; one isolate MIC = 32 μg/ml, I) and tobramycin (19/20 isolates; one isolate MIC > 8 μg/ml, R)....
Biofilm was detected for one strain at a 48 h time point, on a fibrinogen-coated surface; however, it is not known whether this clinical isolate forms biofilm on abiotic surface, whether it expresses the truncated or full-length Scl1.3 protein, and whether it produces an unknown fibrinogen-...
stop– If specified, it must be a list of strings. Text generation stops if any one of the specified strings is generated. You can specify any subset of these parameters while invoking an endpoint. Next, we show an example of how to invoke an endpoint with these arguments...
Text generation stops if any one of the specified strings is generated. You can specify any subset of these parameters while invoking an endpoint. Next, we show an example of how to invoke an endpoint with these arguments. Code completion The following examples demonstrate how ...
Peak Season Lead Time: one month Product Attributes Specification Material:Food Grade Silicone+PP; Shape:High Bottle; Product Name:Silicone Travel Bottle; Size:91*54*38mm / 118*54*38mm; Weight:25g / 20g; Color:Mulitcolor or Customized; ...
Peak Season Lead Time: one monthOff Season Lead Time: within 15 workdays Peak Season Lead Time: one month Product Attributes Specification Type:Surgical Supplies Materials; Material:Stainless Steel; Ethylene Oxide Sterilization:Co.60 Sterilization; ...