We examined vascular amyloid-beta deposition and other abnormalities in the posterior cerebral artery of consecutive cases of Alzheimer's disease (AD) compared to controls. Smooth muscle atrophy was a consistent feature in the cases of AD examined (p<0.01) and was surprisingly independent of adjacen...
Sarcopenia is a term originally coined in reference to the decline of muscle mass with aging. However, in recent times this term is being used operationally in many clinical disciplines (e.g., cancer cachexia) to define a level of muscle atrophy independent of aging per se. It is argued ...
Infants and children in the growth stage of malnutrition may have obvious developmental delay. Long-term insufficient nutrient intake or absorption and digestion dysfunction may result in insufficient nutrition for bones, brains an...
Muscle atrophy occurs when the degradation rate is higher than the synthesis rate during diabetes. Here, we hypothesized that diabetes induces skeletal muscle autophagy, however, if this increased autophagy becomes chronic, autophagy-mediated cell death occurs that could then contribute to skeletal ...
Muscle disuse leads to a considerable loss in skeletal muscle mass and strength. However, the cellular mechanisms underlying disuse-induced muscle fibre atrophy remain to be elucidated. Therefore we assessed the effect of muscle disuse on the CSA (cross-sectional area), muscle fibre size, satellite...
- 《Muscle & Nerve》 被引量: 67发表: 1994年 Phenotypic and molecular insights into spinal muscular atrophy due to mutations in BICD2 Abstract Spinal muscular atrophy is a disorder of lower motor neurons, most commonly caused by recessive mutations in SMN1 on chromosome 5q. Cases without ......
42. A段落大意题。 根据“A-myo-trophic comes f rom the Greek language. "A" means no or neg ative. "Myo" refers to muscle, and "T rophic" means nourishment--"No muscle nourishmen t."..."Lateral" identifies the areas...("sclerosi s") in the region"可知,第二段主要介绍了"AL S...
When muscles no longer receive the messages from the motor neurons that they require to function, the muscles begin to atrophy (become smaller). Limbs begin to look "thinner" as muscle tissue atrophies.What Types of Nerves Make Your Body Work Properly?The body has many kinds of nerves. ...
while its expression was upregulated in a fasting condition dataset. In addition, also skeletal muscle-associated genes like muscle atrophy associated gene activating transcription factor 4 (Atf4/ATF4) was downregulated in both spaceflight and aging datasets, while its expression in fasting and exercise...
can cause muscle atrophy and weakness and progressive spastic paralysis, finally died of respiratory failure patients. Now for A L S molecular biology mechanism of the disease and treatment 筋萎缩性侧部硬化症 (A L S) 是A种类脑子的迅速进展,并且脊髓运动神经元退化疾病,可能导致肌肉萎缩和弱点和进步...