Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system of unknown pathogenesis, is a complex disease with a multifactorial etiology determined by both genetic and environmental factors. The pathological entity MS has a wide phenotype, and also the severity of the...
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurological disorder that damages nerve cells and causes disability, as MS does. The exact causes of MS and ALS are not clearly understood, but genetic, environmental, and lifestyle factors are believed ...
About 900 000 people in the US have MS. Onset of symptoms typically occurs at age 20 to 30 years. Women are nearly 3 times more likely to develop MS than men. Other risk factors for MS include certain genetic factors, low vitamin D levels, low levels of sunlight exposure, Epstein-Bar...
This review addresses several areas of contention related to the genetic theory for multiple sclerosis (MS). It is argued (a) that the concept of \{MS\} as a 'complex disease' has little value, (b) just because a disorder is found in multiple families, it is not necessarily genetically...
This observation supports the hypothesis that ''normal'' genes, common to all carriers of the DR15,DQ6,Dw2 haplotype, confer the increased genetic susceptibility to MS associated with this haplotype. 展开 关键词: Humans Multiple Sclerosis Blotting, Southern HLA-DQ Antigens HLA-DR Antigens HLA-...
5. The cause of the disease is unclear; it seems that some people have a genetic Susceptibility(易感性),which is triggered by some unknown environmental factor. Onset(发作)of the disease usually occurs in young adults between the ages of 20 and 40.It is more common in women than men; ...
Researchers have not determined the exact cause of the disease. Common theories suggest the condition is genetic or is triggered by a virus. Currently there is no cure for multiple sclerosis, but there are treatments available to slow the progression of the disease and help maintain normal quality...
Multiple sclerosis, or MS, is a long-term ailment that can influence your optic nerves in your eyed, spinal cord, and the brain I It can cause problems with vision, balance, muscle control, and other basic body functions.
Multiple sclerosis is a complex neurodegenerative disease, thought to arise through autoimmunity against antigens of the central nervous system. The autoimmunity hypothesis fails to explain why genetic and environmental risk factors linked to the disease in one population tend to be unimportant in other...
Around 10,000 people in Austria suffer from multiple sclerosis (MS). It is a disease whose exact cause remains unclear. “It is very likely due to a combination of genetic and environmental factors. But there is no individual 'MS gene’”, said Karl Vass from the University Department of ...