Bempedoic acid is a once daily, oral medication used at a dose of 180 mg. It is a prodrug converted to bempedoyl-CoA by very-long-chain acyl-CoA synthetase-1, an enzyme present within the liver but absent in skeletal muscle, thus eliciting a liver specific action [22]. The active sub...
How safe is NEXLETOL? The safety of bempedoic acid, a component of NEXLETOL, has been studied in4 clinical trialsin more than9,000 people The most common side effects of NEXLETOL in people with high cholesterol include: Symptoms of the common cold or flu-like symptoms, muscle spasms, ...
Bempedoic Acid Reduces LDL-C and is Well-Tolerated in Patients Receiving Atorvastatin 80 mg Background TherapyETC-1002 is an oral, once-daily medication that inhibits adenosine triphosphate citrate lyase, an enzyme upstream of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, to reduce cholesterol ...