Thus, atorvastatin 20 mg is suggested as the first line lipid-lowering agent. Dose titration up to a maximum dose of 80 mg should be done with care, especially at lower eGFR < 30 mL/minute/1.73 m2. Rosuvastatin is a high intensity statin. In CKD stage 1–2, there is no dose ...
statinatorvastatinmyocardial infarctionacute coronary syndromesTo determine the optimal duration of high-intensity atorvastatin therapy post-acute coronary syndrome (ACS). A literature review was conducted using the MEDLINE database (1966-October 2013) and employing the search terms "atorvastatin OR statins...
Results: Significant decreases in LDL (pConclusions: Hip circumference, a surrogate marker of peripheral adiposity, is associated with HDL-cholesterol changes following statin therapy in hypertensive patients. 展开 关键词: Atorvastatin HDL-cholesterol hip circumference hypertension simvastatin ...
These short-term potential burdens and harms of statins, both perceived and real, highlight the importance of individualizing statin therapy so that it is preferentially targeted to the patients who are most likely to live long enough to also experience its benefits. Lee et al12 previously ...
Statins, which act on the liver to prevent cholesterol from forming, are a first-line treatment for high cholesterol. Medications from this class include: Atorvastatin (Lipitor®) Fluvastatin (Lescol®) Lovastatin (Mevacor®, Altoprev®) ...
vi) Angiogenesis inhibitors- angiogenesis (the formation of new blood supplies) is very important to mesothelioma growth. There are many natural compounds can block angiogenesis although some oncologists use the lipophilic statin Lipitor (Atorvastatin) plus a small 75-81 mg aspirin,as the off-label...
To mitigate the risk of atherosclerotic cardiovascular events, statin medications, which inhibit HMG-CoA reductase so as to reduce endogenous cholesterol production, are commonly prescribed to patients with CAD or PAD. Several statins, including atorvastatin, simvastatin, lovastatin, and fluvastatin, are ...
respectively. In the context of a P-gp inhibitor, the respective RBA values for digoxin (344), repaglinide (239), fexofenadine (227), and atorvastatin (190) were higher than 10, thereby suggesting possible transporter involvement in the basolateral membrane. The intracellular unbound concentration ...
CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin Article Open access 10 November 2024 The Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for...
Most patients were White and male, and were receiving moderate- or high-intensity statin therapy (most frequently atorvastatin or rosuvastatin). Few patients (< 10%) were receiving combination therapy of statin and ezetimibe. Approximately 60% of patients achieved their 2016 ESC/EAC LDL-C goals...