This compound kills clinical strains of multidrug-resistant fungi including Candida spp., Cryptococcus neoformans, Cryptococcus gattii and Aspergillus fumigatus. (Gly0.8Nap0.2)20 shows superior performance compared with amphotericin B by showing not only potent antifungal activities but also high antifungal ...
The hypothetical role played by the intracellular formation of reactive oxygen species (ROS) in the fungicidal action carried out by Amphotericin B (AmB) and Micafungin (MF) was examined in Candida albicans , which remains the most prevalent fungal pathogen. The clinical MICs for MF and AmB ...
Amphotericin B resistance leads to enhanced proteinase and phospholipase activity and reduced germ tube formation in Candida albicans. Fungal Biol. 2010, 114, 189–197. [Google Scholar] [CrossRef] [PubMed] Liesche, J.; Marek, M.; Günther-Pomorski, T. Cell wall staining with Trypan blue ...