Gene encoding a conditionally lethal gene product which activates a purine- or pyrimidine-based prodrug into an agent that is cytotoxic to said metastatic carcinoma; and administering said prodrug to said patientdoi:US5997859 AThe present invention provides recombinant viral vectors carrying a vector ...
There are two different kinds of nucleotides; purines and pyrimidines, which differ based on their chemical structure. The four bases; adenine (A), cytosine (C), guanine (G), and thymine (T), can be grouped into one of the two. Answe...
D. Is Maleic Hydrazide a Pyrimidine or Purine Analogue? Nature 1975, 258, 774-774.Cradwick, P. D. 1975 . Is maleic hydrazide a pyrimidine or purine analogue? Nature 258 : 774 .P. D. Cradwick, Is maleic hydrazide a pyrimidine or purine analogue?, Nature (London) 258 , 774 (1975)....
1. Adenine (A) - Adenine (6-Adminopurine), C5H5N5, is a purine type of nucleobase, containing two rings of alternating carbon and nitrogen atoms. Adenine (A) always pairs with Thymine (T) to form an A-T pair. 2. Cytosine (C) - Cytosine (2-Oxo-4-adminopyrimidine), C4H5N3O,...
apapers are due 纸是交付的[translate] aDo most authentic self. Nothing serious! 做多数地道自已。 严肃的没什么![translate] athe constant diameter of the helix can be explained if the bases in each chain face inward and are restricted so that a purine is always opposite a pyrimidine,avoiding ...
A majority of the mutants identified consistently by both approaches carried a deletion of a gene involved in either the purine or pyrimidine nucleotide biosynthetic pathway and showed a 20- to 1,000-fold drop in viable cell counts as compared to wild-type E. coli after 24 h of growth in ...
DNA is a long string of these blocks or letters. Each nucleotide consists of a sugar (deoxyribose) bound on one side to a phosphate group and bound on the other side to a nitrogenous base. There are two classes of nitrogen bases called purines (double-ringed structures) and pyrimidines (...
1. Concentrations of purine and pyrimidine ribonucleotides were measured with HPLC in lymphocytes of man, horse, pig and sheep and in rat thymocytes. The A... GJ Peters,RAD Abreu,A Oosterhof,... - 《Biochimica Et Biophysica Acta》 被引量: 99发表: 1983年 Improved synthesis of 2'-deoxyfor...
g Crystal violet assay for the viability of MDA-MB-231 cells preincubated with pyrimidines or purines, followed by treatment with SPA or LM-2I (mean ± s.d., n = 6 biologically independent experiments). ** P < 0.01, ***P < 0.001, NS: not significant (P > ...
A DNA triplex is formed when pyrimidine or purine bases occupy the major groove of the DNA double Helix forming Hoogsteen pairs with purines of the Watson-... MD Frank-Kamenetskii,SM Mirkin - 《Annual Review of Biochemistry》 被引量: 1018发表: 1995年 The HeLa Pur factor binds single-stra...