aHuman actions, not live 人的行动,不居住[translate] a对不起我没有听明白你的意思 正在翻译,请等待...[translate] aEGFR is expressed on the cell surface of normal cells and cancer cells. EGFR 关于正常的细胞和癌细胞的细胞表面被表达。[translate]...
Previous researches have demonstrated the meaning of CTSB for the progress of several tumors, whereas few clues about its immunological characteristic in gliomas. Here we systematically explored its biologic features and clinical significance for gliomas
M2d macrophages support tumor cell immune evasion via emitting immunosuppressive substances like IL-10 and PD-1, inhibiting normal immune responses. By encouraging tumor growth, invasion, and angiogenesis, they aid in the advancement of tumors. Table 1 Comparison of markers and biological functions ...
AURKA is predominantly recognized as a mitotic kinase, however, recent findings have uncovered an equally important role of interphasic AURKA in normal cells. In contrast, in cancer tissues, AURKA is overexpressed in a cell-cycle-independent manner and is mislocalized in the cytoplasm and/or nucle...
angiogenesis (the process by which tumors send out signals to induce surrounding normal tissues to grow new blood vessels into the tumor). In addition, PEITC has been demonstrated to inhibit the growth of HER2+ mammary tumors in mice and inhibitmetastasisto the brain in a mouse model of ...
Breast cancer-related effects of eating mustard Mustard isothiocyanates AITC and PEITC have been shown to have anti-breast cancer properties in a number of studies. For example, oral administration of AITC has been demonstrated to restore levels ofproliferationandaromatase activityto near normal levels...
In preclinical models, low and high ECAD expression differentially associated with sensitivity to topoisomerase, aurora, and HSP90 inhibitors, and EGFR inhibitors. E-cadherin protein expression is a robust prognostic biomarker with potential clinical utility in CRC. Abbreviations 5-FU 5-fluorouracil ...
Besides, 20 normal oral mucosa were obtained and all tissues samples were half frozen for RNA and DNA extraction, and half fixed in 10% formalin and embedded in paraffin. The current study was authorized by the Institutional Ethics Committee of the West China Medical Center, Sichuan University,...
its possible contribution to disease pathogenesis, we deep sequenced miRNAs from purified cells of a total of six TCRαβ+ CD8+ T-LGL patients and five sorted age-matched healthy control CD8+ TEMRA cell fractions as the closest normal counterpart cell, using a next-generation sequencing approach...
M. F. A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants. Science 238, 542–545 (1987). CAS PubMed Google Scholar Hunter, J. C. et al. Biochemical and structural analysis of common cancer-associated KRAS mutations. Mol. Cancer Res. 13, 1325...