An average eGFR varies by age, but in younger adults who are considered healthy, a range of 80-120mL/min/1.73 m2is generally normal. GFR decreases as you get older, but a reduced GFR can cause similar issues in older adults as in those who are younger. Adecrease in GFR could also b...
Kidney decline is often permanent, leading to the need for dialysis or an organ transplant. That’s why two blood tests—one for creatinine and another for eGFR—are crucial steps in any diagnosis: Creatinine Creatinine is a waste product of muscle metabolism that your kidneys should filter out...
Figure 1. Tablet of brigatinib Mechanism of Action Brigatinib is a potent tyrosine kinase inhibitor that effectively inhibits various kinases involved in cancer progression. It targets crucial proteins such as ALK, ROS1, IGF-1R, FLT-3, and certain EGFR mutations. By blocking the phosphorylation...
Glioblastoma multiforme (GBM) is a primary brain tumor that is very aggressive, resistant to treatment, and characterized by a high degree of anaplasia and proliferation. Routine treatment includes ablative surgery, chemotherapy, and radiotherapy. However, GMB rapidly relapses and develops radioresistance...
The invasion properties of glioblastoma hamper a radical surgery and are responsible for its recurrence. Understanding the invasion mechanisms is thus critical to devise new therapeutic strategies. Therefore, the creation of in vitro models that enable t
Looking for online definition of GFR or what GFR stands for? GFR is listed in the World's most authoritative dictionary of abbreviations and acronyms
When it comes to cancer, except for blood cancer, it is generally diagnosed by biopsy. However, there is a way to diagnose cancer without a biopsy. Radiopharmaceuticals are the answer.The frontrunner in the Korean radiopharmaceutical market is DuoChemBio
Glomerular filtration rate (GFR) and estimation of the GFR (eGFR) in adults: the GFR is the best overall measure of renal function Because theS-Crresults were traceable to IDMS, we used the reexpressed 4-v MDRD equation (14). [4] Nonstandard abbreviations: CKD, chronic kidney disease; ...
Introduction Epidermal growth factor receptor (EGFR) is frequently amplified, overexpressed, and mutated in multiple cancers. In normal cell physiology, EGFR signaling controls cellular differentiation, proliferation, growth, and survival. During tumorigenesis, mutations in EGFR lead to increased kinase activ...
Some common mutations include EGFR and PDL1 forlung cancer; and BRCA1 and BRCA2 for breast andovarian cancers. Stage, Grade, or Type The “stage” of your cancer is a measure of how far your cancer has spread. The “grade” of your tumor is a measure of how different the cells are...