Their structures were elucidated by means of a combination of homo- and heteronuclear 2D-NMR techniques (COSY, TOCSY, NOESY, ROESY, HSQC, and HMBC), and by FAB-MS. The new compounds were characterized as (3β,16α)-28-{[O-β-D-glucopyranosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O...
1 NMR structural determination of evybactin in DMSO-d6. a, 1H. b, 13C. c, COSY. d, ROESY. e, 1H-13C HSQC. f, 1H-13C HMBC. Extended Data Fig. 2 2D NMR key correlations for evybactin structural assignment. All correlations were measured in DMSO-d6 except for the HMBC ...
Their structures were determined by spectroscopic analyses, including 2D-NMR (COSY, HMQC, HMBC, and NOESY) and high-resolution electrospray ionization mass spectrometry (HRESIMS). Cytotoxic and anti-inflammatory activities of these compounds were evaluated. Compound...
1H-NMR spectroscopic studies of paramagnetic superstructured ironIII porphyrinsThis article is dedicated to the memory of Professor Michel Momenteau of Institut Curie.Abbreviations. 1D and 2D: one-dimensional and two-dimensional; COSY: correlated spectroscopy; NOESY: nuclear Overhauser effect spectroscopy;...
There are an estimated 150 million affected individuals worldwide, of whom a large proportion remains undiagnosed because of a lack of specific symptoms early in this disorder and inadequate diagnostics. In this study, NMR-based metabolomic analysis in conjunction with uni- and multivariate statistics...
ms at 7 T) can improve spectral resolution and reduce spectral overlap82,89leading to 100% specificity and sensitivity for 2HG detection, but the method can lead to quantification errors due to the longer TE90. An alternative approach is the use of a 2D correlation spectroscopy (COSY)...
Sequence specific assignment was obtained for all but three HN backbone 1 H resonances and for more than 95% of the 1 H side-chain resonances using a combination of 1 H 2D NOESY; TOCSY and COSY experiments at 293K. The structure was calculated on the basis of four disulfide bridge ...
Their structures were elucidated by means of a combination of homo- and heteronuclear 2D-NMR techniques (COSY, TOCSY, NOESY, ROESY, HSQC, and HMBC), and by FAB-MS. The new compounds were characterized as (3β,16α)-28-{[O-β-D-glucopyranosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O...
Legionella pneumophila infects eukaryotic cells by forming a replicative organelle – the Legionella containing vacuole. During this process, the bacterial protein DrrA/SidM is secreted and manipulates the activity and post-translational modification (PT
NMR (1D 1H and 13C, 2D COSY, TOCSY, PFGHMQC, and PFGThe ecdysteroid content of Silene claviformis has been analyzed and the four major compounds have been identified as 20-hydroxyecdysone, 2-deoxy-20-hydroxyecdysone, 2-deoxyecdysone, and integristerone A. Two new minor compounds have also...