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The receptor (FGFR2b) binding specificity is an essential element in regulating the diverse functions of FGF10. Analyzing the FGF10:FGFR2b complex we found that Thr-114 in β4 of FGF10 could form specific interactions with D3 of FGFR2b. To investigate the role of Thr-114 played on ...
The vertebrate kidney is an architecturally intricate organ composed of nephron functional units that cleanse the circulation of metabolic waste and maintain fluid homeostasis1. Nephrons contain a blood filter, a segmented epithelial tubule, and collecting duct2. The blood filter disperses fluid across ...
(Tb), body composition and ageing are complex, and not fully resolved. In particular, Tband metabolic rate often change in parallel, making disentangling their effects difficult. Here we show that in both sexes of mice and hamsters exposure to a temperature of 32.5 °C leads to a ...
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private const string BasePath = @"a:\"; // The below is returned to the user as a version private const string Version = "1.0.0"; Because of the prefixed @ this string ends at the trailing " by ignoring the escape character \ and as such should be counted as 2 code lines and ...
Pregnant women, participants of not-white ethnicity, those with type 1 diabetes for less than one year, those on dialysis or with renal transplantation, those with a prior history of viral hepatitis or cirrhosis of any etiology as well those with significant alcohol intake (≥ 2 alcohol ...
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